Utilisation of Chimeric Lyssaviruses to Assess Vaccine Protection against Highly Divergent Lyssaviruses [PDF]
Viruses, 2018 Lyssaviruses constitute a diverse range of viruses with the ability to cause fatal encephalitis known as rabies. Existing human rabies vaccines and post exposure prophylaxes (PEP) are based on inactivated preparations of, and neutralising antibody ...
Jennifer S. Evans +6 more
doaj +8 more sources
Phylogeographic Aspects of Bat Lyssaviruses in Europe: A Review [PDF]
Pathogens, 2023 During the last few decades, bat lyssaviruses have become the topic of intensive molecular and epidemiological investigations. Since ancient times, rhabdoviruses have caused fatal encephalitis in humans which has led to research into effective strategies
Heliana Dundarova +10 more
doaj +2 more sources
Comparative Neutralization Activity of Commercial Rabies Immunoglobulin against Diverse Lyssaviruses [PDF]
Vaccines, 2023 Novel lyssaviruses, the causative agents of rabies, continue to be described mostly due to increased surveillance in bat hosts. Biologicals for the prevention of rabies in humans have, however, remained largely unchanged for decades.
Jessica Coertse +3 more
doaj +2 more sources
Discovery of a novel bat lyssavirus in a Long-fingered bat (Myotis capaccinii) from Slovenia. [PDF]
PLoS Neglected Tropical Diseases, 2023 Lyssaviruses are the causative agents of rabies, a zoonotic, fatal disease that is thought to be ancestral to bats. In the last decade, the detection of bat associated lyssaviruses is increasing also in Europe.
Danijela Černe +5 more
doaj +2 more sources
Development of broad‐spectrum human monoclonal antibodies for rabies post‐exposure prophylaxis [PDF]
EMBO Molecular Medicine, 2016 Currently available rabies post‐exposure prophylaxis (PEP) for use in humans includes equine or human rabies immunoglobulins (RIG). The replacement of RIG with an equally or more potent and safer product is strongly encouraged due to the high costs and ...
Paola De Benedictis +19 more
doaj +5 more sources
Genomic and Clinical Analysis of a Fatal Human Lyssavirus irkut Case: Evidence for a Natural Focus in the Russian Far East [PDF]
VirusesIn this report, we document and analyze a case in which the Irkut virus (IRKV) (Mononegavirales: Rhabdoviridae) caused a fatal human case following a bat bite in June 2021.
Ekaterina Klyuchnikova +21 more
doaj +2 more sources
The Challenge of Lyssavirus Infections in Domestic and Other Animals: A Mix of Virological Confusion, Consternation, Chagrin, and Curiosity [PDF]
PathogensLyssaviruses are RNA viruses in the Family Rhabdoviridae, Genus Lyssavirus. They represent the causative agents of acute, progressive encephalitis, known historically as rabies.
Charles E. Rupprecht +5 more
doaj +2 more sources
Multipurpose Passive Surveillance of Bat-Borne Viruses in Hungary: Lyssaviruses and Filoviruses in Focus [PDF]
AnimalsBats are vital parts of ecosystems but also act as important reservoirs of viruses that can infect humans. Studying bat-borne viruses is essential for preventing spillover events, and passive surveillance offers a promising, bat-friendly approach.
Anna Szabó +10 more
doaj +2 more sources
Evaluation of Taxonomic Characteristics of Matlo and Phala Bat Rabies-Related Lyssaviruses Identified in South Africa [PDF]
Viruses, 2023 We report the genetic characterization of two potentially novel rabies-related lyssaviruses identified from bats in Limpopo province, South Africa. Matlo bat lyssavirus (MBLV) was identified in two Miniopterus natalensis (Natal long-fingered) bats in ...
Natalie Viljoen +3 more
doaj +2 more sources
Detection and Serological Evidence of European Bat Lyssavirus 1 in Belgian Bats between 2016 and 2018 [PDF]
Tropical Medicine and Infectious DiseaseLyssaviruses are neurotropic viruses capable of inducing fatal encephalitis. While rabies virus has been successfully eradicated in Belgium, the prevalence of other lyssaviruses remains uncertain.
Inne Nauwelaers +6 more
doaj +2 more sources