Results 81 to 90 of about 26,398 (197)
S1‐Guideline for diagnosis and therapy of necrobiosis lipoidica
Summary Necrobiosis lipoidica (NL) is a rare granulomatous skin disease of unknown etiology that occurs frequently in association with diabetes mellitus and other comorbidities. The predilection site is the lower leg, particularly the pretibial areas. The exact pathogenesis remains unclear.
Cornelia Erfurt‐Berge +6 more
wiley +1 more source
Senescent fibroblasts construct collagen fibrils, whose orientation is disturbed. We found that senescent fibroblasts downregulate C‐pp cleavage enzymes BMP‐1 and PCPE‐1, which results in downregulation of C‐pp cleavage. This was demonstrated by conducting BMP‐1 knockdown experiments in young fibroblasts, which led to a disturbance in the orientation ...
Koji Moriya +3 more
wiley +1 more source
Arterial tortuosity syndrome (ATS) is a recessively inherited connective tissue disorder, mainly characterized by tortuosity and aneurysm formation of the major arteries.
Barnhoorn, Sander +14 more
core +1 more source
The present study characterized newt digital flexor tendon regeneration structurally at both micro‐ and nanoscales following complete transection and suggested that the mechanism of tissue regeneration differs between the early phase (until 6 weeks) and the late phase (after 6 weeks). Tendon stubs remained separated for up to 2 weeks after transection,
Tomoka Kamiya +7 more
wiley +1 more source
LOX and LOXL2 Expression in Canine Mammary Carcinomas
ABSTRACT Mammary tumours account for approximately 50% of the neoplasms in female dogs. Even conventionally accepted prognostic indicators often fail to reliably predict the clinical behaviour of these tumours, underscoring the need for more effective prognostic markers.
Jessika Daniel +6 more
wiley +1 more source
Incisional Hernia Development: Wound Healing Gone Wrong?
ABSTRACT Incisional hernia (IH) is a common complication of abdominal surgeries, characterised by the protrusion of abdominal contents through a weakened surgical scar. Despite advancements in surgical techniques and biomaterials, IH remains a significant clinical and economic burden, with recurrence rates reaching up to 32% after repair.
Asim A. Abbas +3 more
wiley +1 more source
How reliable and robust are current biomarkers for copper status? [PDF]
Cu is an essential nutrient for man, but can be toxic if intakes are too high. In sensitive populations, marginal over- or under-exposure can have detrimental effects.
Araya, Magdalena +6 more
core
Frontiers of antifibrotic therapy in systemic sclerosis [PDF]
Although fibrosis is becoming increasingly recognized as a major cause of morbidity and mortality in modern societies, targeted anti-fibrotic therapies are still not approved for most fibrotic disorders. However, intense research over the last decade has
Abraham, DJ +5 more
core
Downregulation of lysyl oxidase protects retinal endothelial cells from high glucose–induced apoptosis [PDF]
Kim, Dongjoon +3 more
core +2 more sources

