A step-by-step in crystallo guide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase. [PDF]
J Biol Chem, 2018 Williams AH +7 more
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Turnover of Bacterial Cell Wall by SltB3, a Multidomain Lytic Transglycosylase of Pseudomonas aeruginosa. [PDF]
ACS Chem Biol, 2016 Lee M +6 more
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The synthesis and evaluation of novel soluble lytic transglycosylase inhibitors
Lytic transglycosylases (LTs) present an attractive target of antibiotics due to their unique function in bacterial cell growth and division. They act on peptidoglycan (PG) by creating spaces via non-hydrolytic reactions to facilitate insertion of cell-envelop spanning structures that the cell requires for PG biosynthesis and recycling.
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Structure and cell wall cleavage by modular lytic transglycosylase MltC of Escherichia coli. [PDF]
ACS Chem Biol, 2014 Artola-Recolons C +14 more
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Cloning, expression, and characterization of a peptidoglycan hydrolase from the phage ST79 [PDF]
core +1 more source
The Predicted Lytic Transglycosylase HpaH from Xanthomonas campestris pv. vesicatoria Associates with the Type III Secretion System and Promotes Effector Protein Translocation. [PDF]
Infect Immun, 2017 Hausner J +3 more
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Phage Therapy in Bacterial Infections Treatment: One Hundred Years After the Discovery of Bacteriophages [PDF]
core +1 more source
Immunoinformatics-based design and evaluation of a multi-epitope vaccine against Vibrio fluvialis. [PDF]
Sci RepNaveed M +9 more
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