Results 141 to 150 of about 2,643 (172)
The bacterial septal ring protein RlpA is a lytic transglycosylase that contributes to rod shape and daughter cell separation in Pseudomonas aeruginosa. [PDF]
Jorgenson MA +4 more
europepmc +1 more source
Immunoinformatics-based design and evaluation of a multi-epitope vaccine against Vibrio fluvialis. [PDF]
Naveed M +9 more
europepmc +1 more source
Structural Insights into MltC from <i>Acinetobacter baumannii</i>: Conservation of the Catalytic Residue and Flexibility in Substrate Recognition. [PDF]
Jang H, Kim CM, Park HH.
europepmc +1 more source
‘Holy’ proteins II: the soluble lytic transglycosylase
Enzymes involved in the metabolism of the bacterial cell wall peptidoglycan are excellent targets for antibiotics. Penicillins and related beta-lactam antibiotics inhibit the enzymes that act on the peptide cross-links of the peptidoglycan. The X-ray structure of the transglycosylase revealed a two-layered ring of alpha-helices in a right-handed ...
Bauke W Dijkstra +1 more
exaly +4 more sources
Although cleaving the same glycosidic bond between MurNAc and GlcNAc in murein, lytic transglycosylases differ from lysozymes by catalyzing an intramolecular transglycosylation of the glycosyl-bond onto the C6 hydroxyl group of the muramic acid residue yielding 1.6-anhydromuramic acid-carrying products.
Höltje, J., J.-V. Höltje
openaire +4 more sources
The lytic transglycosylases of Escherichia coli are involved in peptidoglycan metabolism and resemble the lysozymes not only in activity, but in the case of the 70 kDa soluble lytic transglycosylase (Slt70), also structurally.
W Keck
exaly +2 more sources
Purification, crystallization and preliminary X-ray analysis of the lytic transglycosylase MltA fromEscherichia coli [PDF]
The lytic transglycosylase MltA from Escherichia coli with its membrane anchor and signal sequence deleted has been purified to homogeneity by means of cation-exchange chromatography.
Bauke W Dijkstra +2 more
exaly +2 more sources
Lytic transglycosylases cleave the β-(1 → 4)-glycosidic bond in the bacterial cell wall heteropolymer peptidoglycan between the N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues with the concomitant formation of a 1,6 ...
Christopher W Reid, Anthony J Clarke
exaly +2 more sources

