Results 121 to 130 of about 432,438 (233)
, 2008 Nous rapportons un cas d’hyperthyroïdie par métastases osseuses sécrétantes autonomisées de cancer vésiculaire thyroïdien différencié chez un patient de 65 ans. Il s’agit d’une situation exceptionnelle.
BOUTAHRI, Mohammed
core
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
, 2016 Introduction : La survenue de métastases cérébrales est un événement fréquent dans l’histoire naturelle des carcinomes bronchiques. La Radiothérapie en condition Stéréotaxique (SRS) et la neurochirurgie demeurent les traitements standards pour les ...
Omeiri, Amer
core +1 more source
Métastases osseuses : physiopathologie, prise en charge thérapeutique et clinique
, 2019 L’apparition de métastases osseuses est souvent synonyme de stade tardif dans les cancers. Du fait de leur gravité elles sont un problème de santé publique majeur puisqu’elles engendrent une détérioration de la qualité de vie des patients. Elles ont pour
El Habhab, Farah
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Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang +4 more
wiley +1 more source
Copine‐4 Paraneoplastic Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang +12 more
wiley +1 more source
PCGF1 Promotes the Tumorigenesis of Malignancies Through Upregulating CCDC34 in Glioma
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Polycomb group factor 1 (PCGF1) and coiled‐coil domain‐containing protein 34 (CCDC34) have been implicated in tumorigenesis in multiple malignancies. However, their biological functions and prognostic significance in glioma remain poorly defined.
Yuanbing Chen +7 more
wiley +1 more source
, 2018 Dans le cadre de la pathologie du cancer, les métastases constituent la cause principale de mortalité puisque ces dernières sont associées à 90% des cas de décès de patients souffrant de la maladie.
Donati, Kim
core +1 more source
Arthritis Care &Research, Accepted Article.Objective Existing patient‐reported outcome (PRO) measures for systemic sclerosis (SSc) have important limitations, including inadequate coverage of early disease and limited inclusion of diffuse cutaneous (dcSSc) and limited cutaneous (lcSSc) subtypes.
George J. Greene +5 more
wiley +1 more source