Results 31 to 40 of about 402,861 (200)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The Pan African Medical Journal, 2013 Le mélanome anorectal est une tumeur rare représentant 1,5 % de tous les mélanomes et moins de1 % des cancers anorectaux. Son pronostic est redoutable à cause de la survenue précoce de métastases.
Rachid Bouchentouf +3 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Métastases intramédulaires d'un adénocarcinome pulmonaire: à propos d'un cas
The Pan African Medical Journal, 2015 Les métastases de la moelle épinière sont extrêmement rares. Elles surviennent chez 0,1 à 0,4% des patients cancéreux et représentent 1% de toutes les tumeurs de la colonne vertébrale et 1-3% des tumeurs intramédullaires.
Hicham Naji-Amrani +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Métastases cutanées vues au laboratoire d'anatomie pathologique à Lomé, Togo entre 2005 et 2014
The Pan African Medical Journal, 2015 INTRODUCTION: l'objectif de cette étude était de documenter le profil épidémiologique et histologique des métastases cutanées vues au laboratoire d'anatomie pathologique (LAP) de Lomé.
Tchin Darre +6 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Métastases cutanées révélant un carcinome indifférencié du nasopharynx (UCNT)
The Pan African Medical Journal, 2017 Les cancers du nasopharynx, dominés par les carcinomes épidermoïdes surtout de type undifferenciated carcinoma of nasopharyngeal type (UCNT), sont des tumeurs particulières au sein des autres cancers de la sphère ORL par leurs évolutivité, le haut ...
Jamal Fatihi, Salah Bellasri
doaj +1 more source
A Simple Scoring System Predicting the Survival Time of Patients with Bone Metastases after RT. [PDF]
PLoS ONE, 2016 This study aimed to develop a scoring system to predict the survival time of patients with bone metastases after radiation therapy (RT). The scoring system can guide physicians to a better selection of appropriate treatment regimens.The medical records ...
Wen-Yi Zhang +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source