Results 51 to 60 of about 410,566 (200)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Nocardia vinacea infection with septic articular involvement and tenosynovitis

BMC Infectious Diseases
Nocardiosis, typically affecting immunocompromised patients, can manifest in rare forms like hand tenosynovitis. We report a 91-year-old man with Nocardia vinacea, confirmed by genetic sequencing after negative cultures, likely caused by a gardening ...
Axel Tabary, Oana Dumitrescu, Elisabeth Hodille, Claire Triffault Fillit, Cyrille B. Confavreux, Emmanuel Massy   +5 more
doaj   +1 more source

Les métastases ovariennes d'origine biliaire: 2 cas avec revue de la littérature

The Pan African Medical Journal, 2013
Les ovaires constituent un site fréquent de métastases. L'origine gastrique prédomine. Les métastases ovariennes d'origine biliaire sont rarement rapportées dans la littérature.
Imane Kamaoui, Mustapha Maaroufi, Benjalloun el Bachir, Hanane Ouzaa, Siham Tizniti   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Métastase cérébrale d'un carcinome du col utérin

The Pan African Medical Journal, 2013
Les métastases cérébrales des cancers du col de l'utérus sont extrêmement rares. Elles sont généralement supra-tentorielles, survenant à un stade avancé de la maladie et dans un cadre de néoplasie polymétastatique. La tumeur primitive est le plus souvent
Tarik Chekrine, Abdeslam Hassouni, Hassan Jouhadi, Souha Sahraoui, Zineb Bouchbika, Amina Taleb, Nadia Benchakroun, Nezha Tawfiq, Abdellatif Benider   +8 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Pneumothorax spontané secondaire post opératoire compliquant une paralysie récurrentielle

The Pan African Medical Journal, 2014
Le Pneumothorax spontané est défini par un épanchement gazeux de la grande cavité pleurale en dehors de tout traumatisme ou manipulation instrumentale. Son incidence est estimée à 28/100000 pour les hommes et 6/100000 pour les femmes. Les étiologies sont
Toufik Joulali, Ali Derkaou, Abdelkarim Shimi, Mohammed Khatouf   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Carcinome urothélial sur un calice rénal exclu révélé par une métastase cérébrale

The Pan African Medical Journal, 2019
Ce Corrigendum vise à rectifier l´oubli d´un nom d´auteur dans la liste d'auteurs de l´article original « Carcinome urothélial sur un calice rénal exclu révélé par une métastase cérébrale ». Pan Afr Med J. 2019;34:184.
The Pan African Medical Journal
doaj   +1 more source