Wnt5a Regulates Embryonic Müllerian Duct Development Through the Non-Canonical Wnt PCP Pathway [PDF]
CellsMüllerian anomalies are anatomical variations of the female reproductive tract resulting from the incomplete development of the embryonic Müllerian ducts.
Isaac Kyei-Barffour +3 more
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Persistent Mullerian Duct Syndrome in an Adult Infertile Male: A Case Report [PDF]
Journal of Nepal Medical AssociationPersistent Müllerian duct syndrome is a rare autosomal recessive disorder of sex development characterized by the presence of Müllerian duct derived structures in a normally virilized, genotypical (46, XY) and phenotypical male.
Nesuma Sedhain +3 more
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The Genetic Landscape of Müllerian Duct Anomalies: A Comprehensive Review [PDF]
Reproductive Medicine and BiologyBackground Müllerian duct anomalies (MDAs) are developmental malformations of the female genital tract that present as a series of abnormalities within the reproductive tracts of females.
Lin He +6 more
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Fortuitous Persistent Müllerian Duct Syndrome Diagnosis in an Adult Patient With Hematuria: A Case Report [PDF]
Clinical Case ReportsPersistent Müllerian duct syndrome is a genetic disorder. It consists of Müllerian duct remains due to improper anti‐Müllerian hormone. Early life presentation is often associated with undescended testes or inguinal hernias.
Alexi Boitsios +3 more
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An atypical Müllerian duct anomaly: Duplicated cervices and vaginas with a single uterine cavity [PDF]
Radiology Case Reports, 2023 Müllerian duct anomalies include a wide variety of developmental abnormalities involving the female reproductive system, many of which are not adequately represented by the current classification system used in the United States.
Ryan Narbutas, MD +4 more
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Mini review: Asymmetric Müllerian duct development in the chicken embryo [PDF]
Frontiers in Cell and Developmental BiologyMüllerian ducts are paired embryonic tubes that give rise to the female reproductive tract. In humans, the Müllerian ducts differentiate into the Fallopian tubes, uterus and upper portion of the vagina.
Juan L. Tan +2 more
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Anti-Müllerian Hormone Signal Transduction involved in Müllerian Duct Regression [PDF]
Frontiers in Endocrinology, 2022 Over seventy years ago it was proposed that the fetal testis produces a hormone distinct from testosterone that is required for complete male sexual development.
Richard L. Cate
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Persistent Müllerian Duct Syndrome: Understanding the Challenges [PDF]
Case Reports in Urology, 2022 Persistent Müllerian duct syndrome (PMDS) is a rare autosomal recessive condition defined by the presence of Müllerian duct-derived structures in an otherwise normally masculinized phenotypical and genotypical (46,XY) male.
Irene Chua, Naeem Samnakay
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Distal-less homeobox genes Dlx5/6 regulate Müllerian duct regression
Frontiers in Endocrinology, 2022 Dlx5 and Dlx6 encode distal-less homeodomain transcription factors that are present in the genome as a linked pair at a single locus. Dlx5 and Dlx6 have redundant roles in craniofacial, skeletal, and uterine development.
Rachel D. Mullen +3 more
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Frontiers in Cell and Developmental Biology, 2022 A transgenic mouse approach using bacterial artificial chromosomes (BAC) was used to identify regulatory regions that direct Müllerian duct expression for Amhr2 and Osterix (Osx, also known as Sp7). Amhr2 encodes the receptor that mediates anti-Müllerian
Malcolm M. Moses +8 more
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