Results 41 to 50 of about 8,023 (216)
Veterinary Dermatology, Volume 36, Issue 4, Page 453-461, August 2025.Background – Canine atopic dermatitis (cAD) is a chronic, inflammatory, multifactorial and pruritic disease. The presence of skin barrier impairment (e.g. filaggrin alterations), along with abnormal immune responses, can negatively impact cutaneous barrier function.
Wendie Roldan Villalobos +5 more
wiley +1 more source
Ixazomib が奏効している心アミロイドーシス合併多発性骨髄腫 [PDF]
, 2019 Ixazomib は，経口のプロテアソーム阻害薬であり，特に非注射薬の組み合わせが選択される多発性骨髄腫患者の再発難治例にとって有用な治療薬である．今回，我々はIxazomib が奏効している心アミロイドーシス合併多発性骨髄腫を経験したため報告する．症例は50歳代女性で，20XX 年10月心不全精査のため当院循環器内科入院となり，精査にて洞不全症候群（type3），心アミロイドーシスと診断された．洞不全症候群（type3）に対して心臓ペースメーカー移植術が施行され，血液検査にてM ...
HAYASHI Shigeki +11 more
core +2 more sources
New Phytologist, Volume 247, Issue 2, Page 504-517, July 2025.Summary Repetitive DNA is a feature of all organisms, ranging from archaea and plants to humans. DNA repeats can be seen both in coding and in noncoding regions of the genome. Due to the recurring nature of the sequences, simple DNA repeats tend to be more prone to errors during replication and repair, resulting in variability in their unit length ...
Sridevi Sureshkumar +3 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2006 目的建立急性脊髓损伤双向凝胶电泳图谱,初步观察急性脊髓损伤组织中蛋白质组的变化与差异表达,为进一步探讨急性脊髓损伤分子机制奠定了基础。方法采用双向凝胶电泳分离脊髓总蛋白,银染显色,Image Master图象分析系统分析,从胶中选取分离蛋白质点,基质辅助激光解析电离飞行时间质谱（MALDI-TOF-MS）分析获取肽质量指纹图谱（PMF）,Mascot软件搜索MSDP、SWISS-PROT数据库鉴定蛋白质。结果获得重复性和分辨率较好的脊髓双向凝胶电泳图谱。质谱分析了12个蛋白质点,获取6张肽质量指纹图谱 ...
赵宝林 +6 more
doaj
Systematic Entomology, Volume 50, Issue 3, Page 495-518, July 2025.Using genomic data from 285 species across 19 planthopper families, we conducted the first phylogenomic study targeting global planthoppers and inferred their phylogeny with the highest resolution so far. We proposed taxonomic changes including the establishment of a new family Borysthenidae stat. rev. and a new superfamily Meenoploidea superfam.
Junchen Deng +9 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2007 目的对62例多发性骨髓瘤（MM）患者免疫固定电泳（immunofixation electrophoresis,IFE）、血清蛋白电泳及免疫球蛋白定量结果进行分析,以探讨M蛋白、MM型别分布及其在MM中的临床诊断价值。方法血清蛋白和免疫固定电泳:采用全自动快速电泳分析系统进行电泳和扫描;免疫球蛋白定量:采用BECKMAN-COULTER IMAGE免疫化学分析仪,以速率散射比浊法分析,检测各样本的免疫球蛋白（IgGI、gMI、gA）含量。结果62例MM全部检出M带 ...
郑伟 +4 more
doaj
Distinct cytokine-inducing ability of Streptococcus pyogenes strains isolated from toxic shock-like syndrome cases [PDF]
, 2008 新潟大学博士（医学）新潟大学平成20年3月24日新大院博（医）第1198号新大院博（医 ...
49618, 筒井, 奈々子
core
Zhongguo shiyan zhenduanxue, 2011 目的利用Au蛋白芯片（proteinchip gold array）技术检测肾损伤患者尿蛋白指纹图谱,探讨其灵敏、快速预测和评估肾损伤的临床应用价值。方法利用表面增强激光解析电离飞行时间质谱（surface-enhanced laser desorption-ionization time of flight mass spectrometry,SELDI-TOF-MS）技术及Au蛋白芯片检测477例尿蛋白指纹图,包括237例肾病患者和240例对照者。利用生物标志模型软件（biomarker ...
姜伟 +7 more
doaj
基于蛋白质组学技术探讨7-羟乙基白杨素防治高原脑水肿的作用靶点
浙江大学学报. 医学版目的 研究7-羟乙基白杨素（7-HEC）治疗大鼠高原脑水肿的作用靶点及机制。 方法 54只雄性Wistar大鼠随机分为正常对照组、模型对照组和7-HEC组，每组18只。后两组于实验第4天置于模拟7000
张 冬梅 +5 more
doaj +1 more source