Results 131 to 140 of about 1,572,263 (313)
Row‐to‐column impedance of an N × M matrix circuit [PDF]
, 1987 Howard C. Nedderman
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Estimates for the minimum eigenvalue of an M-matrix [PDF]
, 2023 Qin Zhong, Ling Li
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Matrix Completion from Fewer Entries: Spectral Detectability and Rank Estimation
, 2015 The completion of low rank matrices from few entries is a task with many practical applications. We consider here two aspects of this problem: detectability, i.e.
Krzakala, Florent +2 more
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Inverse M-matrix completions of patterns omitting some diagonal positions
Linear Algebra and its Applications, 2000 Let \(N= \{1,\dots, n\}\). The author investigates the following question: Which subsets \(Q\) of \(N\times N\) have the property that whenever \(a_{ij}\) for \((i,j)\in Q\) form a ``partial inverse \(M\)-matrix'' (i.e., \(a_{ij}\geq 0\) and if \(L\times L\subseteq Q\), then the inverse of \(\{a_{ij}:i, j\in L\}\) is an \(M\)-matrix), \(a_{ij}\) can be
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Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
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Efficient Structured Matrix Recovery and Nearly-Linear Time Algorithms\n for Solving Inverse Symmetric $M$-Matrices [PDF]
, 2018 Arun Jambulapati +2 more
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Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source