Results 131 to 140 of about 1,396,823 (294)
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli+15 more
wiley +1 more source
Lower bounds on the minimum eigenvalue of the Fan product of several M-matrices
The concept of the Fan product of several M-matrices is introduced. Furthermore, two new lower bounds of the minimum eigenvalue of the Fan product of several M-matrices are proposed.
Qin Zhong
doaj +1 more source
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren+8 more
wiley +1 more source
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran+3 more
wiley +1 more source
The Role of Glycosylation in the Secretion of Proteoglycans
Neung-Seon Seo+2 more
doaj +1 more source
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel+3 more
wiley +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji+3 more
wiley +1 more source
M-Matrix Inverse problem for distance-regular graphs
We analyze when the Moore–Penrose inverse of the combinatorial Laplacian of a distance–regular graph is a M–matrix;that is, it has non–positive off–diagonal elements or, equivalently when the Moore-Penrose inverse of the combinatorial Laplacian of a distance–regular graph is also the combinatorial Laplacian of another network.
Bendito Pérez, Enrique+3 more
openaire +2 more sources
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley +1 more source
Erratum: T. Yasuda, A.R. Poole, M. Shimizu, T. Nakagawa, S.M. Julovi, H. Tamamura, N. Fujii, T. Nakamura. Involvement of CD44 in Induction of Matrix Metalloproteinases by a COOH‐Terminal Heparin‐Binding Fragment of Fibronectin in Human Articular Cartilage in Culture. Arthritis & Rheumatism 2003;48(5):1271–1280. [PDF]
Niek de Vries+4 more
openalex +1 more source