Results 111 to 120 of about 19,797,232 (311)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 1998 The chapters in this book thoroughly cover the structure, regulation, and function of matrix metalloproteinases, and provide information on the latest strategies to inhibit enzyme activity.
Mecham, Robert P., Parks, William C.
core
Singular graph and extension of jordan chains of an M-Matrix
Linear Algebra and its Applications, 1996 Let \(S\) be a singular graph. This paper investigates conditions on the vertices of \(S\) to extend Jordan chains for the generalized nullspace of each minus \(M\)-matrix with singular graph \(S\). The conditions are the interlevel, the strong interlevel, and the strong predecessor property.
Cantó, Rafael, Climent, Joan-Josep
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
M-matrix characterizations.I—nonsingular M-matrices
Linear Algebra and its Applications, 1977 AbstractThe purpose of this survey is to classify systematically a widely ranging list of characterizations of nonsingular M-matrices from the economics and mathematics literatures. These characterizations are grouped together in terms of their relations to the properties of (1) positivity of principal minors, (2) inverse-positivity and splittings, (3)
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
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, 2018 Matrix of 53 dental characters and 13 paromomyid ...
Sergi López-Torres (7061078) +1 more
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A sufficient condition for the existence of an M-matrix with prescribed spectrum
Computers & Mathematics with Applications, 2001 The inverse spectrum problem for \(M\)-matrices is studied. This problem involves finding necessary and sufficient conditions for an \(n\)-tuple of complex numbers to be the spectrum of an \(n\times n\) \(M\)-matrix. A sufficient condition is determined for the existence of \(M\)-matrices of low order with a prescribed spectrum.
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M-matrix asymptotics for Sturm–Liouville problems on graphs
Journal of Computational and Applied Mathematics, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Currie, Sonja, Watson, Bruce A.
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
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