Results 101 to 110 of about 1,573,587 (265)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
, 2018 This book belongs to a series of online books summarizing the recent state Topological Geometrodynamics (TGD) and its applications. TGD can be regarded as a unied theory of fundamental interactions but is not the kind of unied theory as so called GUTs constructed by graduate students at seventies and eighties using detailed recipes for how to reduce ...
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Erasure Recovery Matrices for Data Erasures and Rearrangements
MathematicsWhen studying signal reconstruction, the frames are often selected in advance as encoding tools. However, in practical applications, this encoding frame may be subject to attacks by intermediaries and generate errors. To solve this problem, in this paper,
Miao He, Changtian Wu, Jinsong Leng
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
On some geometric properties of sequence spaces of generalized arithmetic divisor sum function
Journal of Inequalities and ApplicationsRecently, some new sequence spaces ℓ p ( A α ) $\ell _{p}(\mathfrak{A}^{\alpha })$ ( 0 < p < ∞ ) $(0 ...
Mohammad Mursaleen, Elvina Herawati
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Inverse M-matrix completions of patterns omitting some diagonal positions
Linear Algebra and its Applications, 2000 Let \(N= \{1,\dots, n\}\). The author investigates the following question: Which subsets \(Q\) of \(N\times N\) have the property that whenever \(a_{ij}\) for \((i,j)\in Q\) form a ``partial inverse \(M\)-matrix'' (i.e., \(a_{ij}\geq 0\) and if \(L\times L\subseteq Q\), then the inverse of \(\{a_{ij}:i, j\in L\}\) is an \(M\)-matrix), \(a_{ij}\) can be
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FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source