Results 131 to 140 of about 378,588 (317)

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

British Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen, Fariha Balouch, Claire Reilly, Christopher Burgess, Peter Lewindon   +4 more
wiley   +1 more source

Pleuropneumonectomy for the treatment of tuberculosis

Вестник хирургии имени И.И. Грекова
The OBJECTIVE was to reduce the risk of complications and mortality after pleuropneumonectomy in patients with pulmonary tuberculosis complicated by pleural empyema.METODS AND MATERIALS.
D. B. Giller, A. A. Popova, V. A. Basangova, G. V. Shcherbakova, S. S. Saenko, O. Sh. Kesaev, V. V. Koroev, I. I. Martel, S. V. Smerdin, A. E. Ergeshov   +9 more
doaj   +1 more source

Whole genome sequencing of Mycobacterium tuberculosis reveals slow growth and low mutation rates during latent infections in humans

, 2014
Very little is known about the growth and mutation rates of Mycobacterium tuberculosis during latent infection in humans. However, studies in rhesus macaques have suggested that latent infections have mutation rates that are higher than that observed ...
Vic L Arcus, Noel Karalus (533380), Coley, Kathy, Marchiano, Emily, David Alland, Karalus, Noel, Shannon D. Manning (148732), Ray T Cursons, Manning, Shannon D., Ray T. Cursons (533378), David Alland (31640), Alland, David, Noel Karalus, Emily Marchiano, Roberto Colangeli, Kathy Coley, Cursons, Raymond T., Emily Marchiano (533383), Vic L. Arcus (533377), Roberto Colangeli (31628), Soyeon Kim (533382), Colangeli, Roberto, Ali Ruthe (533379), Ruthe, Ali, Ali Ruthe, Kathy Coley (533381), Soyeon Kim, Arcus, Vickery L., Shannon D Manning, Kim, Soyeon   +29 more
core   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

Sulfate metabolism in M. tuberculosis

The FASEB Journal, 2006
Mycobacterial pathogens have been declared a global emergency by the World Health Organization, particularly in regard to the deadly synergy of M. tuberculosis and M. avium with HIV infection. The emergence of multidrug resistant strains of both
openaire   +1 more source

Second worldwide proficiency study on variable number of tandem repeats typing of Mycobacterium tuberculosis complex

, 2014
Global Network for the Molecular Surveillance of Tuberculosis 2010: A. Miranda (Tuberculosis Laboratory of the National Institute of Health, Porto, Portugal)BACKGROUND: The quality of variable number of tandem repeats (VNTR) typing of Mycobacterium ...
Global Network for the Molecular Surveillance of Tuberculosis 2010, Ködmön, C., de Beer, J.L., de Beer, J. L., van Soolingen, D., van Ingen, J., Supply, P., Network For Molecular Surveillance of Tuberculosis 2010 (collaborators), Global   +7 more
core   +1 more source

Adverse events in bedaquiline‐ and pretomanid‐based regimens for drug‐resistant tuberculosis from trial, implementation and pharmacovigilance studies

British Journal of Clinical Pharmacology, EarlyView.
Abstract The availability of safety data, particularly concerning adverse events (AEs) associated with the new shorter regimen for drug‐resistant tuberculosis (TB) containing a bedaquiline–pretomanid‐based regimen, is still limited. This systematic review aims to provide a comprehensive and updated analysis of AEs related to this new regimen by ...
Nisa Maria, Annisa Lazuardi Larasati, Indri Yuliani Hamdani, Jin‐Gun Cho, Jan‐Willem C. Alffenaar   +4 more
wiley   +1 more source

XPERT MTB/RIF TEST FOR THE DIAGNOSIS OF TUBERCULOSIS AND RIFAMPICIN RESISTANCE: RESULTS OF ITS INTRODUCTION IN THE KYRGYZ REPUBLIC

Туберкулез и болезни лёгких, 2014
The Xpert MTB/RIF analysis was used to test 3,829 autopsy specimens. The detection rate of rifampicin-resistant tuberculosis averaged 13%. The fact that the detection rate of patients with multidrug-resistant tuberculosis was 5% among the new cases with ...
A. D. Adambekova, D. A. Adambekov, V. I. Litvinov   +2 more
doaj  

Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood, Sarah Bannister, Stephen Duffull, April Martinez, Sarath Ranganathan, Shivanthan Shanthikumar, Amanda Gwee   +6 more
wiley   +1 more source

Defining critical concentrations of the second line TB drugs (cycloserin and PAS), to establish drug susceptibility testing on the liquid medium of Middlebrook 7Н9

Туберкулез и болезни лёгких, 2016
In order to determine critical concentrations of the second line TB drugs, namely cycloserin and PAS, and to use these critical concentrations for establishment of drug susceptibility testing by the proportional method on the liquid medium of Middlebrook
E. S. Dyuzhik, N. V. Kaunetis, T. G. Smirnova, E. E. Larionova, G. V. Volchenkov, L. N. Chernousova   +5 more
doaj