First insights into the genetic composition of <i>M. tuberculosis</i> population circulating in Kosovo. [PDF]
Minias A +16 more
europepmc +1 more source
Chalkophore-mediated respiratory oxidase flexibility controls <i>M. tuberculosis</i> virulence. [PDF]
Buglino JA +5 more
europepmc +1 more source
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu +4 more
wiley +1 more source
Updated Erdman reveals tandem repeat copy number is phase-variable and impacts <i>M. tuberculosis</i> adaptation across evolutionary timescales. [PDF]
Modlin SJ +6 more
europepmc +1 more source
Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh +2 more
wiley +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Subpopulations in clinical samples of <i>M. tuberculosis</i> can give rise to rifampicin resistance and shed light on how resistance is acquired. [PDF]
Brunner VM, Fowler PW.
europepmc +1 more source
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Corrigendum to "Recombinant BCGΔBCG1419c protects outbred mice against M. tuberculosis challenge" [Vaccine 61 (2025) 127347]. [PDF]
Kurtz SL +3 more
europepmc +1 more source

