Results 191 to 200 of about 378,588 (317)

A tiled amplicon protocol for culture-free whole-genome sequencing of <i>M. tuberculosis</i> from clinical specimens. [PDF]

J Clin Microbiol
Kalinich CC, Gonzalez FL, Osmaston A, Breban MI, Distefano I, Leon C, Coronel J, Tan G, Crudu V, Ciobanu N, Codreanu A, Solano W, Ráez J, Sheen P, Zimic M, Allicock OM, Chaguza C, Wyllie AL, Brandt M, Weinberger DM, Sobkowiak B, Cohen T, Grandjean L, Grubaugh ND, Redmond SN.   +24 more
europepmc   +1 more source

A New Method for the Isolation of M. tuberculosis

American Journal of Public Health and the Nations Health, 1956
openaire   +3 more sources

Bio‐guided fractionation of (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid from Abelmoschus sagittifolius root as a potent α‐glucosidase inhibitor: An integrated in vitro and in silico study

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Abelmoschus sagittifolius stands out as a valuable medicinal source for developing functional food targeting type 2 diabetes. This study investigated the α‐glucosidase inhibitory potential of an active fraction obtained from A. sagittifolius roots (ASR), enriched in (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid (OA), using both enzyme ...
Nguyen Phuong Mai, Nguyen Van Quan, Nguyen Dang Duc, Tran Dang Xuan   +3 more
wiley   +1 more source

The ubiquitin ligase CBL and Fas-associated factor 2 cooperate to regulate the innate immune response to M. tuberculosis. [PDF]

PLoS Pathog
Truong T, Ray A, Martin K, Bates NA, Salemi M, Phinney BS, Penn BH.   +6 more
europepmc   +1 more source

JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series

JEADV Clinical Practice, EarlyView.
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni, Francois Rosset, Isotta Giunipero di Corteranzo, Lorenzo Bellando, Rebecca Senetta, Simone Ribero, Pietro Quaglino   +6 more
wiley   +1 more source

Patterns of compensatory mutations in rpoA/B/C genes of multidrug resistant M. tuberculosis in Uganda. [PDF]

PLoS One
Kateete DP, Namakula S, Kigozi E, Katabazi FA, Kasule GW, Musisi K, Wampande E, Lukoye D, Joloba ML.   +8 more
europepmc   +1 more source

Selectivity of the Time-Dependent <i>M. tuberculosis</i> LeuRS Inhibitor Ganfeborole Is Driven by Target Vulnerability. [PDF]

ACS Chem Biol
Wang M, He Y, Cohen SA, Strohm AR, Shetye G, Franzblau SG, Walker SG, Alley MRK, Tonge PJ.   +8 more
europepmc   +1 more source

Prevalence and Clinical Variants of Scabies at Mbarara Regional Referral Hospital, Uganda

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Scabies affects an estimated 200 million people globally. Despite its designation as a neglected tropical disease by the WHO in 2017, local data on its burden remain scarce. Objectives To assess the prevalence and describe clinical variants of scabies infestation amongst patients seen at Mbarara Regional Referral Hospital (MRRH ...
Abraham Mukalazi, Stephen Kizito Mirembe, Grace Mulyowa Kitunzi, Aloyo Gladys Onguti, Esther Awino   +4 more
wiley   +1 more source

A point-mutated Ag85B antigen improves recombinant bacterial expression and protects mice from aerosol M. tuberculosis challenge. [PDF]

Vaccine
Hsu WL, Jiao Y, Hvasta M, Tran KN, Troyer BT, Huang WC, Kuhlman B, Obregon-Henao A, Lovell JF.   +8 more
europepmc   +1 more source

Beyond Skin and Eyes: The Medical and Social Burden of Oculocutaneous Albinism in Africa: A Narrative Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni, Niccolò Capurro, Alessandro Svizzero, Valeria Brazzelli   +3 more
wiley   +1 more source