Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang +3 more
wiley +1 more source
Human iPSC-derived alveolar macrophages reveal macrophage subtype functions of itaconate in M. tuberculosis defense. [PDF]
Krebs AS +21 more
europepmc +1 more source
Association between periodontitis and exudative retinal detachment: A population‐based cohort study
Abstract Background To investigate whether periodontitis, a common bacterial‐induced inflammatory condition, serves as a risk factor for exudative retinal detachment (ERD), which results from fluid entering the subretinal space due to damage to the retinal pigment epithelium or leaky intraocular vessels, typically associated with inflammatory ...
Earl Fu +5 more
wiley +1 more source
Influence of Diabetes Mellitus on the Development of Multidrug-Resistant Tuberculosis (MDR-TB) in Relation With Genetic Mutations of <i>M. tuberculosis</i> Isolates in Ethiopia. [PDF]
Seid A, Nureddin S.
europepmc +1 more source
Abstract We report a patient with Hoyeraal–Hreidarsson syndrome (HHS), a telomere biology disorder, who developed severe chronic enterocolitis with inflammatory bowel disease‐like features. Vedolizumab led to improvement in stool frequency, reduced fecal calprotectin, and clinical remission without infectious complications.
Yasutaka Chiba +6 more
wiley +1 more source
A New Method for the Isolation of M. tuberculosis
openaire +3 more sources
Macronutrient and micronutrient profiles of meat types: insights into human health and diet
Abstract Despite considerable advances in global health and nutrition, emerging challenges such as population growth, climate change, and limited natural resources continue to threaten food security. Meat remains an essential component of the human diet, supplying high‐quality proteins, essential amino acids, lipids, vitamins, and minerals necessary ...
Özgül Anitaş +4 more
wiley +1 more source
Tamoxifen inhibits histidine kinases of <i>M. tuberculosis</i> two-component signaling systems. [PDF]
Garg A +4 more
europepmc +1 more source
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni +3 more
wiley +1 more source
Adaptive immunity shapes baseline physiology of <i>M. tuberculosis</i> in high-dose versus low-dose infection BALB/c mouse drug treatment models. [PDF]
Hendrix J +11 more
europepmc +1 more source

