Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins +8 more
wiley +1 more source
Distribution and transmission of M. tuberculosis in a high-HIV prevalence city in Malawi: A genomic and spatial analysis. [PDF]
Chitwood MH +23 more
europepmc +1 more source
Abstract Background In England, transmission of Mycobacterium bovis between cattle and certain species of free‐roaming, wild deer has been implicated in some endemic bovine tuberculosis (bTB) regions. However, there are still data and knowledge gaps regarding the role of deer in the epidemiology of this disease.
Rachel Jinks +12 more
wiley +1 more source
Deconvoluting drug interactions using <i>M. tuberculosis</i> physiologic processes: transcriptional disaggregation of the BPaL regimen <i>in vivo</i>. [PDF]
Wynn EA +10 more
europepmc +1 more source
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang +5 more
wiley +1 more source
Evaluating selection at intermediate scales within genes provides robust identification of genes under positive selection in M. tuberculosis clinical isolates. [PDF]
Ioerger TR, Shatby A.
europepmc +1 more source
Low‐ and middle‐income countries (LMICs) account for 90% of all deaths from injury globally, yet health systems remain poorly equipped to manage the escalating trauma burden. This study highlights a critical and escalating operative trauma burden in Malawi, driven largely by road traffic injuries, particularly motorcycle taxis.
Cornelius Mukuzunga +6 more
wiley +1 more source
Trehalose dimycolate inhibits phagosome maturation and promotes intracellular <i>M. tuberculosis</i> growth via noncanonical SNARE interactions. [PDF]
Santamaria C +11 more
europepmc +1 more source
Experimental assessment of large mammal population estimates from airborne thermal videography
Wildlife resource management requires reliable, fast, and affordable methods of surveying wildlife populations to develop and adaptively adjust policies. Thermal video from drones can yield high rates of detection over large areas with relative speed and safety.
Julia S. McElhinny +7 more
wiley +1 more source
Guselkumab Safety in Patients With Latent Tuberculosis: Analysis of 11 Studies in Psoriatic Disease
ABSTRACT Certain psoriatic disease treatments, including tumor necrosis factor‐α inhibitors (TNFi), increase tuberculosis (TB) risk. Testing for latent TB infection (LTBI) before initiating systemic therapy has been standard practice for psoriasis (PsO) patients; however, updated consensus states routine testing is not required before initiating ...
Luis Puig +14 more
wiley +1 more source

