Results 141 to 150 of about 1,738,596 (334)

Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype

open access: yesNature Communications, 2018
Resetting tumor-associated macrophages (TAMs) is a promising strategy to ameliorate the immunosuppressive tumor microenvironment and improve innate and adaptive antitumor immunity.
Degao Chen   +16 more
semanticscholar   +1 more source

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

open access: yesAdvanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández   +7 more
wiley   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

The functional form of the demand for euro area M1 [PDF]

open access: yes
A remarkable development seen in recent years is the pronounced decline in euro area M1 velocity vis--vis a moderate decline in short-term interest rates, which represent the most natural opportunity cost for M1, suggesting an increase in the interest ...
Stracca, Livio
core  

Reduced contribution of the ipsilateral primary motor cortex to force modulation with short-term motor learning in humans: An NIRS study [PDF]

open access: yes, 2008
How is muscle force modulated during hand exercise? Oxygenation in the contralateral primary motor cortex (M1) has been observed to vary considerably across trials of repetitive handgrip exercise.
Kenichi Shibuya   +2 more
core   +1 more source

M1 Resonances in Unstable Magic Nuclei

open access: yes, 1993
Within a microscopic approach which takes into account RPA configurations, the single-particle continuum and more complex $1p1h\otimes phonon$ configurations isoscalar and isovector M1 excitations for the unstable nuclei ${56,78}$Ni and ${100,132}$Sn are
A.B. Migdal   +34 more
core   +2 more sources

Effects of Molecular Designs and Double‐Network Morphologies for Bioadhesive Semiconductors

open access: yesAdvanced Functional Materials, EarlyView.
This study establishes molecular‐to‐mesoscale design rules for bioadhesive semiconducting polymers (BASCs). It identifies how side‐chain length, double‐network formation, and film thickness modulate adhesion strength and electronic performance, providing insight into the rational design of intrinsically adhesive semiconductors for stable and efficient ...
Zhichang Liu   +8 more
wiley   +1 more source

4D‐Printable Poly(Thio)urethane Photoresins With Reactive Oxygen Species Responsiveness and Anti‐Inflammatory Functionality

open access: yesAdvanced Functional Materials, EarlyView.
This work introduces UV‐curable poly(thio)urethane (PSU) thermosets as 4D printable scaffolds responsive to oxidative stress. PSU networks with 100 wt.% polypropylene glycol (PPG) effectively suppress inflammatory markers in microglial cells to basal values.
Xabier Lopez de Pariza   +10 more
wiley   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

open access: yesAdvanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

FAKTOR-FAKTOR MAKROEKONOMI YANG MEMPENGARUHI PERMINTAAN UANG DI INDONESIA

open access: yesJurnal Ekonomi & Studi Pembangunan, 2015
: Money demand has an important role for monetary policy authorities in determining appropriate policies to maintain economic stability. Analysis of the demand for money is an economic analysis of the quantities required to support the measures taken by ...
Arif Widodo
doaj  

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