Results 21 to 30 of about 562 (143)
Journal of Social Issues, Volume 78, Issue 4, Page 900-923, December 2022., 2022 Abstract The COVID‐19 pandemic impacted people's lives all over the world, requiring health and safety measures intended to stop the virus from spreading. This study explores whether an unintended consequence of these measures is a new form of ageism. We explore, using qualitative methods, the experiences of older adults living through the pandemic in ...
Elfriede Derrer‐Merk +10 more
wiley +1 more source
, 2020 This deliverable is the second version of the Data Management Plan (DMP) for the Policy Cloud project, provided in month 12 of the project. It provides a description of the project’s datasets according to FAIR principles. The overall purpose of this document is to support the data management lifecycle for all data that will be collected, stored ...
Munné, Ricard +4 more
openaire +2 more sources
A proper motion study of the globular cluster M12 (NGC 6218) [PDF]
Research in Astronomy and Astrophysics, 2018 16 pages, accepted by RAA on May ...
Ing-Guey Jiang +2 more
openaire +4 more sources
Advanced Science, EarlyView.Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng +11 more
wiley +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Introduction Deep brain stimulation (DBS) is an effective treatment for refractory obsessive–compulsive disorder (OCD). Neuropsychological assessment contributes to DBS treatment in several ways: it monitors the cognitive safety of the treatment, identifies beneficial or detrimental cognitive side effects and it could aid to explain ...
Tim A. M. Bouwens van der Vlis +7 more
wiley +1 more source
Advanced Science, EarlyView.As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang +10 more
wiley +1 more source
HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis
Advanced Science, EarlyView.Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim +9 more
wiley +1 more source
Analysis of a Memcapacitor‐Based Online Learning Neural Network Accelerator Framework
Advanced Intelligent Systems, EarlyView.This study introduces a novel CMOS‐based memcapacitor framework for efficient neuromorphic computing, achieving 98.4% accuracy on (MNIST) modified national institute of standards and technology and 85.9% on canadian institute for advanced research( CIFAR)‐10.
Ankur Singh, Dowon Kim, Byung‐Geun Lee
wiley +1 more source
Biomedical Chromatography, Volume 39, Issue 4, April 2025.ABSTRACT Bexicaserin is a highly selective 5HT2c receptor agonist being developed for the treatment of seizures associated with developmental and epileptic encephalopathies (DEEs). We report an LC–MS/MS method for the quantitative estimation of three pharmacologically inactive metabolites (M9, M12, and M20) of bexicaserin in human plasma/urine.
Raja Reddy Kallem +5 more
openalex +2 more sources
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Elexacaftor/tezacaftor/ivacaftor (ETI) is a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) therapy that improves pulmonary function and chronic rhinosinusitis (CRS) in cystic fibrosis (CF) adults with at least one copy of the F508del CFTR mutation.
Margaux Petitjean +16 more
wiley +1 more source