Results 51 to 60 of about 23,145 (194)
Engineered Phagemids for Nonlytic, Targeted Antibacterial Therapies [PDF]
, 2015 The increasing incidence of antibiotic-resistant bacterial infections is creating a global public health threat. Because conventional antibiotic drug discovery has failed to keep pace with the rise of resistance, a growing need exists to develop novel ...
Collins, James J. +3 more
core +1 more source
Loss of R Factors Promoted by Bacteriophage M13 and the M13 Carrier State [PDF]
Journal of Bacteriology, 1972 The infection of different Hfr strains ofEscherichia colibearing derepressed R factors of the fi+or fi−type can result in the loss of the R factor and the conversion of the infected cells to the R−state. This extends earlier observations on the elimination of F′ factors by bacteriophage M13 infection.
S E, Russell, V N, Iyer
openaire +2 more sources
Advanced Science, EarlyView.We report an electrochemical biosensor that employs biopanning‐derived affinity peptides as selective receptors on a multifunctional chitosan–zwitterionic–gold nanoparticle (CS–ZI–AuNPs) nanohydrogel interface. The CS–ZI–AuNPs nanohydrogel exhibits antifouling properties, abundant sites for stable peptide immobilization, and efficient electrochemical ...
Hyo Jeong Yang +6 more
wiley +1 more source
大腸菌を用いたフォスファカン（コンドロイチン硫酸プロテオグリカン）の融合コア蛋白の発現条件の検討 [PDF]
, 1996 Optimal conditions for expressing a specific region of core protein of phosphacan, a chondroitin sulfate proteoglycan known as receptor type protein tyrosine phosphatase, as fusion protein with glutathione S-transferase (GST) in E.coli were examined. DNA
Ito, Sekiko, Okamoto, Motoi
core +1 more source
SmartBot, EarlyView.DNA machinery represents a burgeoning frontier at the intersection of robotics and nanotechnology, evolving from static nanostructure toward dynamic nanorobots. Here, the authors review the comprehensive research pipeline of designer DNA‐based nanomachines, covering the design, analysis, and fabrication. These programmable systems enable transformative
Yiquan An +5 more
wiley +1 more source
Unlocking the M13 (F1) virion : investigation into the role of pIII C domain of F specific filamentous bacteriophage in infection : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]
, 2005 Filamentous phage adsorb to the host cells by binding of the N2 domain of pIII to the tip of the F pilus. Binding of N1 domain of pIII to the secondary receptor (Tol A), triggers the opening of the virion by a poorly understood mechanism.
Bennett, Nicholas James
core
Studies on Bacteriophage M13 DNA. 1. A Cleavage Map of the M13 Genome [PDF]
European Journal of Biochemistry, 1975 A physical map of the bacteriophage M13 genome has been constructed on the basis of specific cleavage of M13 replicative form DNA by bacterial restriction endonucleases. The 13 fragments produced by the enzyme from Haemophilus aphirophilus (endonuclease R.Hap II) as well as the 10 fragments produced by the enzyme from Haemophilus aegyptius ...
C A, Van Den Hondel, J G, Schoenmakers
openaire +2 more sources
Microbiology and Immunology, EarlyView.ABSTRACT The extensive and indiscriminate use of antibiotics, which are intended to halt bacterial growth or eliminate them, has unintentionally given rise to antimicrobial resistance (AMR), which is a critical threat to global health. In the pursuit of alternative solutions, researchers have focused on type II toxin–antitoxin systems prevalent within ...
Hana Hasegawa +6 more
wiley +1 more source
Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]
, 2007 A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Alicia Aguilar +54 more
core +1 more source
Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen +4 more
wiley +1 more source