Results 131 to 140 of about 180,585 (312)

Discovery of PIPE-359, a Brain-Penetrant, Selective M₁ Receptor Antagonist with Robust Efficacy in Murine MOG-EAE. [PDF]

ACS Med Chem Lett, 2021
Schrader TO, Xiong Y, Lorenzana AO, Broadhead A, Stebbins KJ, Poon MM, Baccei C, Lorrain DS.   +7 more
europepmc   +1 more source

Probing Cellular Activity Via Charge‐Sensitive Quantum Nanoprobes

Advanced Materials, EarlyView.
A new quantum sensing modality detects shifts in zero‐field splitting caused by charge rearrangement with diamond nanocrystals in response to cellular activity. These electric‐field‐driven effects provide an alternative to temperature‐based interpretations, enabling real‐time, single‐cell readout of inflammation.
Uri Zvi, Shivam Mundhra, David Ovetsky, Qing Chen, Aidan R. Jones, Stella Wang, Maria J. Román‐Vazquez, Marie Kim, Udoka M. Ibeh, Michele Ferro, Kunle Odunsi, Marina C. Garassino, Michael E. Flatté, Melody A. Swartz, Denis R. Candido, Aaron Esser‐Kahn, Peter C. Maurer   +16 more
wiley   +1 more source

Effects of muscarinic M₁ receptor stimulation on reinforcing and neurochemical effects of cocaine in rats. [PDF]

Neuropsychopharmacology, 2020
Weikop P, Jensen KL, Thomsen M.
europepmc   +1 more source

Analysis of CD8+ T cell-mediated anti-viral responses in mice with targeted deletions of the M1 or M5 muscarinic cholinergic receptors

, 2007
Vaiva Vezys, David Masopust, Maxime Desmarets, Jürgen Wess, James C. Zimring   +4 more
openalex   +1 more source

Time-dependent modulation of muscarinic m1/m3 receptor signalling by local anaesthetics [PDF]

, 2013
Susanne Picardi, Markus F. Stevens, Klaus Hahnenkamp, Marcel E. Durieux, Philipp Lirk, Markus W. Hollmann   +5 more
openalex   +1 more source

Strain Engineering of Magnetoresistance and Magnetic Anisotropy in CrSBr

Advanced Materials, EarlyView.
Biaxial compressive strain significantly enhances magnetoresistance and critical saturation fields in thin flakes of the 2D magnet CrSBr, along all three crystallographic axes. First‐principles calculations link these effects to strain‐induced increases in exchange interactions and magnetic anisotropy.
Eudomar Henríquez‐Guerra, Alberto M. Ruiz, Marta Galbiati, Álvaro Cortés‐Flores, Daniel Brown, Esteban Zamora‐Amo, Lisa Almonte, Andrei Shumilin, Juan Salvador‐Sánchez, Ana Pérez‐Rodríguez, Iñaki Orue, Andrés Cantarero, Andres Castellanos‐Gomez, Federico Mompeán, Mar Garcia‐Hernandez, Efrén Navarro‐Moratalla, Enrique Diez, Mario Amado, José J. Baldoví, M. Reyes Calvo   +19 more
wiley   +1 more source

Hit-to-lead investigation of a series of novel combined dopamine D2 and muscarinic M1 receptor ligands with putative antipsychotic and pro-cognitive potential

, 2012
Anette Sams, Krestian Larsen, Gitte Kobberøe Mikkelsen, Morten Hentzer, Claus T. Christoffersen, Klaus Gjervig Jensen, Kristen Frederiksen, Benny Bang‐Andersen   +7 more
openalex   +1 more source

Differential S1P Receptor Profiles on M1- and M2-Polarized Macrophages Affect Macrophage Cytokine Production and Migration [PDF]

, 2017
Jan Uwe Müller, Wolfram von Bernstorff, Claus-Dieter Heidecke, Tobias Schulze   +3 more
openalex   +1 more source

Mixed‐Metal Promotion in a Manganese‐Molybdenum Oxynitride as Catalyst to Integrate C─C and C─N Coupling Reactions for the Direct Synthesis of Acetonitrile from Syngas and Ammonia

Advanced Materials, EarlyView.
Transition metal oxy/carbo‐nitrides show great promise as catalysts for sustainable processes. A Mn‐Mo mixed‐metal oxynitride attains remarkable performance for the direct synthesis of acetonitrile, an important commodity chemical, via sequential C─N and C─C coupling from syngas (C1) and ammonia (N1) feedstocks.
M. Elena Martínez‐Monje, Wilson Henao, Tania Rodenas, Patricia Concepción, Virginia Pérez Dieste, Alexander Missyul, Giovanni Agostini, Gonzalo Prieto   +7 more
wiley   +1 more source

Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics

Advanced Materials, EarlyView.
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang, Zehui Lv, Xuejie Cai, Yingjie Wang, Bo Peng, Haojing Xu, Hualuo Pang, Xingdong Yang, Jiawei Xu, Yixin Bian, Bin Feng, Peng Wen, Yufeng Zheng, Xisheng Weng   +13 more
wiley   +1 more source