Results 161 to 170 of about 180,585 (312)

Targeting the muscarinic M1 receptor with a selective, brain-penetrant antagonist to promote remyelination in multiple sclerosis. [PDF]

Proc Natl Acad Sci U S A
Poon MM, Lorrain KI, Stebbins KJ, Edu GC, Broadhead AR, Lorenzana AJ, Roppe JR, Baccei JM, Baccei CS, Chen AC, Green AJ, Lorrain DS, Chan JR.   +12 more
europepmc   +1 more source

Backbone 1H, 13C, 15N chemical shifts of ICL3 from M1 muscarinic cholinergic receptor [Homo sapiens]

Wang, Jiannan, Niu, Xiaogang, Jin, Changwen, Hu, Yunfei   +3 more
openalex   +1 more source

Stimulation of phosphatidylcholine breakdown by thrombin and carbachol but not by tyrosine kinase receptor ligands in cells transfected with M1 muscarinic receptors. Rapid desensitization of phosphocholine-specific (PC) phospholipase D but sustained activity of PC-phospholipase C

, 1992
F R McKenzie, Klaus Seuwen, Jacques Pouysségur   +2 more
openalex   +1 more source

A novel Polymorphism Linked to Epilepsy Encoding a Missense Mutation in the Pre-M1 Region of a6 Subunits Alters the Gating, but not Trafficking, of GABAa Receptors [PDF]

, 2011
Ciria C. Hernández, Katharine N. Gurba, Ningning Hu, Robert L. Macdonald   +3 more
openalex   +1 more source

Untethered Magnetic Microswimmers for Targeted Particle Transport and Flow Manipulation

Advanced Materials Technologies, EarlyView.
This work introduces magnetically actuated microswimmers to dynamically reconfigure fluid flow within a single microfluidic device. Multiple homogeneous microswimmers are independently controlled by an external magnetic field to perform translational and rotational motions, thereby inducing real‐time flow manipulation.
Dineshkumar Loganathan, Dong‐Ming He, Kai‐Wei Chen, Chia‐Yuan Chen   +3 more
wiley   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer. [PDF]

Cell Rep Med
Wang J, Wei J, Pu T, Zeng A, Karthikeyan V, Bechtold B, Vo K, Chen J, Lin TP, Chang AP, Corey E, Puhr M, Klocker H, Culig Z, Bland T, Wu BJ.   +15 more
europepmc   +1 more source

Effects and sites of action of a M1 receptor positive allosteric modulator on colonic motility in rats and dogs compared with 5‐HT₄ agonism and cholinesterase inhibition

, 2020
Yasuhiro Tsukimi, Ruslan V. Pustovit, Andrea M. Harrington, Sonia Garcia‐Caraballo, Stuart M. Brierley, Madeleine R. Di Natale, Juan Carlos Molero, John B. Furness   +7 more
openalex   +2 more sources

An Efficient Diamond Raman Amplification Scheme Based on Adaptive Temporal Synchronization

Advanced Photonics Research, EarlyView.
This work reveals an adaptive temporal synchronization effect in delayed diamond Raman amplification, where the Stokes pulse shifts toward the fundamental peak. A periodic amplification scheme based on this phenomenon enables efficient pump recycling and enhanced energy conversion, offering a robust, delay‐tolerant strategy for advanced nonlinear ...
Hao Zheng, Zhenxu Bai, Hui Chen, Fei Zhang, Chengjin Shi, Jie Ding, Yulei Wang, Zhiwei Lu   +7 more
wiley   +1 more source

The role of m1-cholinergic receptors in associative cortex of young rats in the performing autonomous regulation of heart rate during hypoxic exposure

, 2015
N. M. Volkova
openalex   +2 more sources