Results 181 to 190 of about 3,570 (206)

Absolutely conserved tryptophan in M49 family of peptidases contributes to catalysis and binding of competitive inhibitors

Bioorganic Chemistry, 2009
The role of the unique fully conserved tryptophan in metallopeptidase family M49 (dipeptidyl peptidase III family) was investigated by site-directed mutagenesis on human dipeptidyl peptidase III (DPP III) where Trp300 was subjected to two substitutions (W300F and W300L).
Branka Salopek-Sondi, Dejan Agić, Marija Abramić   +2 more
exaly   +5 more sources

Streptococcus pyogenes Serotyp M49

2011
Streptococcus pyogenes (GAS) ist ein humanpathogenes Bakterium, das eine Reihe von Infektionen beim Menschen auslöst. Ralp3 ist ein zentraler Regulator der ERES-Region. Die Transkriptom- und qRT-PCR-Analysen zeigten, dass die Transkription von 16 Genen in der ralp3-Deletionsmutante signifikant erhöht ist. Integrin-linked Kinase ist ein zentrales Enzym
openaire   +1 more source

Molecular characterization of a major serotype M49 group A streptococcal DNase gene (sdaD)

Infection and Immunity, 1996
Group A streptococci (GAS) express up to four types of secreted DNases. Although GAS infections are correlated with the production of anti-DNase B antibodies, the roles of DNases in the pathogenesis of GAS infections remain unclear. From a lambda library of serotype M49 strain CS101 GAS genome, a 2,147-bp fragment expressing DNase activity on an ...
A, Podbielski, I, Zarges, A, Flosdorff, J, Weber-Heynemann   +3 more
openaire   +2 more sources

Kinetic characterization of arginine deiminase and carbamate kinase from Streptococcus pyogenes M49

Protein Expression and Purification, 2013
Streptococcus pyogenes (group A Streptococcus, GAS) is an important human pathogen causing mild superficial infections of skin and mucous membranes, but also life-threatening systemic diseases. S. pyogenes and other prokaryotic organisms use the arginine deiminase system (ADS) for survival in acidic environments.
Silvio, Hering, Antje, Sieg, Bernd, Kreikemeyer, Tomas, Fiedler   +3 more
openaire   +2 more sources

M49 Avonmouth Junction: Geoarchaeological borehole survey and archaeological evaluation

2018
Wessex Archaeology was commissioned by Galliford Try to undertake a purposive geoarchaeological borehole survey and archaeological evaluation in advance of a proposed new unction and access roads on the M49 near Avonmouth. Fieldwork involved a purposive borehole survey, followed by a second phase of works involving excavation of two archaeological ...
Payne, R, Brown, A
openaire   +1 more source

MPEC 2026-M49 : 2026 MA1

The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
openaire   +1 more source

MPEC 2025-M49 : 2025 MG1

The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
openaire   +1 more source

MPEC 2024-M49 : 2019 GA185

The Minor Planet Electronic Circulars contain information on unusual minor planets, routine data on comets and natural satellites, and occasional editorial announcements. They are published on behalf of Division F of the International Astronomical Union by the Minor Planet Center, Smithsonian Astrophysical Observatory, Cambridge, MA 02138, U.S.A.
openaire   +1 more source

Dietary flavonoids as inhibitors of metallopeptidases of the M49 family

2018
Metallopeptidases of the M49 family are proteolytic enzymes that contain highly conserved HEXXXH motif and whose catalytic activity depends on the zinc cation [1]. Dipeptidyl peptidase III (DPP III) is the best characterized member of this family with distribution detected in almost all forms of life.
Agić, Dejan, Karačić, Zrinka, Špoljarević, Marija, Lisjak, Miroslav, Abramić, Marija   +4 more
openaire   +1 more source

Yeast dipeptidyl peptidase III – insight into the structure of metallopeptidases of M49 family

2009
Dipeptidyl peptidases III (DPP III) are zinc-dependent enzymes that cleave the first two amino acids from N terminus of different length peptides. The DPP III (M49) family is a relatively new metallopeptidase family (MEROPS: the protease database, http://www.merops.ac.uk), whose members are grouped on the basis of their sequence relationships and the ...
Jajčanin Jozić, Nina, Kumar Baral, Pravas, Deller, Sigrid, Macheroux, Peter, Gruber, Karl, Abramić, Marija   +5 more
openaire   +2 more sources