Results 1 to 10 of about 456 (96)
Heliyon, 2022 In this study, we evaluated the correlation between the arginine deiminase (ADI) pathway and nitrogen cycle during cabbage kimchi fermentation. Nitrite used as a food additive can be converted to carcinogenic N-nitroso compounds via reactions with ...
Sera Jung, Ji Yoon Chang, Jong-Hee Lee
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Pegylated Arginine Deiminase Downregulates Colitis in Murine Models [PDF]
Mediators of Inflammation, 2012 Arginine deiminase (ADI), an arginine-metabolizing enzyme involved in cell signaling, is dysregulated in multiple inflammatory diseases and cancers. We hypothesized that pegylated ADI (ADI-PEG) provide protection against colitis. Methods.
Helieh S. Oz +2 more
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Инфекция и иммунитет, 2021 Arginine deiminase is one of three enzymes constituting the arginine deiminase system in bacteria. It was demonstrated that arginine deiminase exerts anti-proliferative effects on some primary and immortalized mouse and human cells.
E. A. Starickova +5 more
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Медицинская иммунология, 2021 Numerous pathogens express arginine deiminase, an enzyme that catalyzes the hydrolysis of L-arginine in a chain of biochemical reactions aimed at the synthesis of ATP in bacterial cells. L-arginine is a semi-essential, proteinogenic amino acid that plays
E. A. Starikova +5 more
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Molecules, 2021 The use of arginine deiminase (ADI) for arginine depletion therapy is an attractive anticancer approach. Combination strategies are needed to overcome the resistance of severe types of cancer cells to this monotherapy.
Zhiying Huang, Haifeng Hu
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Frontiers in Cellular and Infection Microbiology, 2022 Porphyromonas gingivalis is a major pathogenic bacterium involved in the pathogenesis of periodontitis. Citrullination has been reported as the underlying mechanism of the pathogenesis, which relies on the interplay between two virulence factors of the ...
Yoke Chan Chow +8 more
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Regulation of glycolysis and cancer cell proliferation by PKM2 citrullination
Molecular & Cellular Oncology, 2021 Conversion of peptidyl-arginine to peptidyl citrulline, known as citrullination, is a post-translational protein modification catalyzed by the PADI (Protein Arginine Deiminase) family of enzymes. PADI1 and PADI3 catalyze citrullination of arginine 106 in
Sébastien Coassolo, Irwin Davidson
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Regulation of arginine-ornithine exchange and the arginine deiminase pathway in Streptococcus lactis [PDF]
Journal of Bacteriology, 1987 Streptococcus lactis metabolizes arginine by the arginine deiminase (ADI) pathway. Resting cells of S. lactis grown in the presence of galactose and arginine maintain a high intracellular ornithine pool in the absence of arginine and other exogenous energy sources. Addition of arginine results in a rapid release of ornithine concomitant with the uptake
POOLMAN, B, DRIESSEN, AJM, KONINGS, WN
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Медицинская иммунология, 2017 There is a growing body of data about the cytopathic effect of bacterial arginine deiminase on human endothelial cells, but the precise mechanisms of endothelial dysfunction caused by the activity of the enzyme remain poorly understood.
E. A. Starikova +5 more
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Mapping of the arginine deiminase gene in Pseudomonas aeruginosa [PDF]
Journal of Bacteriology, 1982 A mutant of Pseudomonas aeruginosa PAO lacking arginine deiminase activity (arcA) was isolated by screening for a derivative of an arcB mutant (deficient in catabolic ornithine carbamoyltransferase) that did not excrete citrulline under conditions of limited aeration. The arcA mutation was highly cotransducible with arcB.
Mercenier, Annick +3 more
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