Results 41 to 50 of about 106,691 (213)

Hydrogenosome-localization of arginine deiminase in Trichomonas vaginalis [PDF]

Molecular and Biochemical Parasitology, 2011
The arginine dihydrolase (ADH) pathway has an analogous function to the urea cycle in mitochondria-containing cells, by removing nitrogen from amino acids and generating ATP. Subcellular localization of the ADH pathway enzymes in Trichomonas vaginalis revealed that arginine deiminase (ADI) localizes to the hydrogenosome, a mitochondrion-like organelle ...
MORADA M, SMID O, HAMPL V, SUTAK R, LAM B, RAPPELLI, Paola, DESSI', Daniele, FIORI, Pier Luigi, TACHEZY J, YARLETT N.   +9 more
openaire   +3 more sources

Citrullination of Proteins as a Specific Response Mechanism in Plants

Frontiers in Plant Science, 2021
Arginine deimination, also referred to as citrullination of proteins by L-arginine deiminases, is a post-translational modification affecting histone modifications, epigenetic transcriptional regulation, and proteolysis in animals but has not been ...
Claudius Marondedze, Claudius Marondedze, Claudius Marondedze, Giuliano Elia, Ludivine Thomas, Aloysius Wong, Aloysius Wong, Chris Gehring, Chris Gehring   +8 more
doaj   +1 more source

Development of a Pseudomonas aeruginosa Agmatine Biosensor

Biosensors, 2014
Agmatine, decarboxylated arginine, is an important intermediary in polyamine production for many prokaryotes, but serves higher functions in eukaryotes such as nitric oxide inhibition and roles in neurotransmission.
Adam Gilbertsen, Bryan Williams
doaj   +1 more source

Silver Nanoparticles Induce Neutrophil Extracellular Traps Via Activation of PAD and Neutrophil Elastase

Biomolecules, 2021
Silver nanoparticles (AgNPs) are widely used in various fields because of their antimicrobial properties. However, many studies have reported that AgNPs can be harmful to both microorganisms and humans.
HanGoo Kang, Jinwon Seo, Eun-Jeong Yang, In-Hong Choi   +3 more
doaj   +1 more source

Investigation of Arginine deiminase activity in B. cereus and R. eutropha under minimal conditions

, 2023
Prokaryotes form an important part of our lives. These microorganisms, which we can not see with the naked eye, are used in medicine, biotechnology, microbiology and many other fields.
Hüseyin KAHRAMAN, Karaderi, Cennet Canan, Kahraman, Hüseyin, Cennet Canan KARADERİ   +3 more
core   +1 more source

Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface

Cell Reports, 2021
Summary: The arginine deiminase (ADI) pathway has been found in many kinds of bacteria and functions to supplement energy production and provide protection against acid stress.
Yujiro Hirose, Masaya Yamaguchi, Tomoko Sumitomo, Masanobu Nakata, Tomoki Hanada, Daisuke Okuzaki, Daisuke Motooka, Yasushi Mori, Hiroshi Kawasaki, Alison Coady, Satoshi Uchiyama, Masanobu Hiraoka, Raymond H. Zurich, Masayuki Amagai, Victor Nizet, Shigetada Kawabata   +15 more
doaj   +1 more source

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

Arginine deiminase and other antiangiogenic agents inhibit unfavorable neuroblastoma growth: potentiation by irradiation [PDF]

, 2003
In spite of aggressive therapy, children suffering from neuroblastoma have a poor prognosis. Therapeutic failure is most often observed in neuroblastomas with unfavorable features, including amplification/over-expression of the N-myc oncogene, rapid ...
Havers, W., Stuschke, Martin, Gong, H., Pottgen, C., Stuben, G., Pöttgen, Christoph, Gong, Hong, Schweigerer, Lothar, Stuschke, M., Havers, Werner, Stüben, Georg, Schweigerer, Lothar L.   +11 more
core   +1 more source

DEVELOPMENT OF ARGININE DEIMINASE BASED CONDUCTOMETRIC BIOSENSOR FOR ARGININE DETERMINATION

Sensor Electronics and Microsystem Technologies, 2021
For the first time, a conductometric enzyme biosensor was developed to determine arginine concentrations. The bioselective membrane of the biosensor was formed by immobilization of arginine deiminase on the surface of gold planar transducer using covalent crosslinking of glutaraldehyde with bovine serum albumin.
O. O. Soldatkin, I. S. Kucherenko, O. Ya. Sayapina, D. Yu. Kucherenko, S. V. Marchenko, A. P. Soldatkin, S. V. Dzyadevych   +6 more
openaire   +4 more sources

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

Advanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu, Yuwu Chen, Wei Meng, Biyi Xu, Junke Mou, Xiaolin Liu, Mengyang Wang, Qishuo Gu, Qianhui Sun, Man Li, Chen Zhao, Ming Zeng, Ying Lv, Boling Yi, Sheng Qu, Xiaoxuan Bai, Ji Li, Xing Luo, Sining Hu, Bo Yu, Haibo Jia   +20 more
wiley   +1 more source