Results 11 to 20 of about 10,357 (212)
BMC Genomics, 2007 Background So far very limited knowledge exists on L-arginine catabolism in cyanobacteria, although six major L-arginine-degrading pathways have been described for prokaryotes.
Pistorius Elfriede K +4 more
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IMMUNOSUPPRESSIVE EFFECTS OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES
Медицинская иммунология, 2015 Many pathogens use metabolic pathway of arginine for successful dissemination. Bacterial arginine deiminase hydrolyzes arginine to form one molecule of ammonia and two molecules of ATP.
E. A. Starikova +3 more
doaj +3 more sources
Application of Response Surface Methodology for Optimizing Arginine Deiminase Production Medium for Enterococcus faecium sp. GR7 [PDF]
The Scientific World Journal, 2013 Arginine metabolism in Enterococcus faecium sp. GR7 was enhanced via arginine deiminase pathway. Process parameters including fermentation media and environmental conditions were optimized using independent experiments and response surface methodology ...
Baljinder Kaur, Rajinder Kaur
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Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation
Nature Communications, 2020 Protein arginine deiminase 4 (PAD4) facilitates the posttranslational citrullination of histones H3 and H4. Here, the authors provide evidence that PAD4 antagonizes histone methylglyoxal-glycation by rewriting the glycated arginine into citrulline and ...
Qingfei Zheng +2 more
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Медицинская иммунология, 2016 Arginine deiminase is a bacterial enzyme that hydrolyses arginine with citrulline and ammonia formation. In recent years, increasing evidence is reported about in vitro and in vivo anti-angiogenic action of arginine deiminase from Mycoplasma spp.
E. A. Starikova +6 more
doaj +3 more sources
Инфекция и иммунитет, 2018 The protective role of macrophages closely related to the production of bactericidal molecules, in which nitrogen monoxide (NO) play an important role.
E. A. Starikova +6 more
doaj +2 more sources
American Journal of Physiology-Endocrinology and Metabolism, 2021 Pegylated arginine deiminase depletes circulating arginine, but the citrulline generated is utilized by multiple tissues to regenerate arginine and sustain local arginine availability. Preempting the arginine depletion that occurs as result of sepsis and trauma with arginine deiminase offers the possibility of maintaining tissue arginine availability ...
Mahmoud A. Mohammad +4 more
openaire +6 more sources
Streptococcal Arginine Deiminase Inhibits T Lymphocyte Differentiation In Vitro [PDF]
Microorganisms, 2023 Pathogenic microbes use arginine-metabolizing enzymes as an immune evasion strategy. In this study, the impact of streptococcal arginine deiminase (ADI) on the human peripheral blood T lymphocytes function in vitro was studied.
Eleonora A. Starikova +9 more
doaj +2 more sources
Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism. [PDF]
Cell Rep Med, 2022 Obesity is a multi-systemic disorder of energy balance. Despite intense investigation, the determinants of energy homeostasis remain incompletely understood, and efficacious treatments against obesity and its complications are lacking.
Zhang Y +4 more
europepmc +2 more sources
PEGylation increases antitumoral activity of arginine deiminase of Streptococcus pyogenes. [PDF]
Appl Microbiol Biotechnol, 2022 Arginine auxotrophy is a metabolic defect that renders tumor cells vulnerable towards arginine-depleting substances, such as arginine deiminase (ADI) from Streptococcus pyogenes (SpyADI).
Schwarz R +11 more
europepmc +2 more sources