Bioinformatic evaluation of L-arginine catabolic pathways in 24 cyanobacteria and transcriptional analysis of genes encoding enzymes of L-arginine catabolism in the cyanobacterium
Background So far very limited knowledge exists on L-arginine catabolism in cyanobacteria, although six major L-arginine-degrading pathways have been described for prokaryotes.
Pistorius Elfriede K +4 more
doaj +2 more sources
Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation
Protein arginine deiminase 4 (PAD4) facilitates the posttranslational citrullination of histones H3 and H4. Here, the authors provide evidence that PAD4 antagonizes histone methylglyoxal-glycation by rewriting the glycated arginine into citrulline and ...
Qingfei Zheng +2 more
doaj +2 more sources
IMMUNOSUPPRESSIVE EFFECTS OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES [PDF]
Many pathogens use metabolic pathway of arginine for successful dissemination. Bacterial arginine deiminase hydrolyzes arginine to form one molecule of ammonia and two molecules of ATP.
E. A. Starikova +3 more
doaj +2 more sources
The protective role of macrophages closely related to the production of bactericidal molecules, in which nitrogen monoxide (NO) play an important role.
E. A. Starikova +6 more
doaj +2 more sources
Application of Response Surface Methodology for Optimizing Arginine Deiminase Production Medium for Enterococcus faecium sp. GR7 [PDF]
Arginine metabolism in Enterococcus faecium sp. GR7 was enhanced via arginine deiminase pathway. Process parameters including fermentation media and environmental conditions were optimized using independent experiments and response surface methodology ...
Baljinder Kaur, Rajinder Kaur
doaj +2 more sources
A ROLE OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES M49-16 IN PROMOTING INFECTION AND INHIBITION OF ENDOTHELIAL CELL PROLIFERATION [PDF]
Arginine deiminase is a bacterial enzyme that hydrolyses arginine with citrulline and ammonia formation. In recent years, increasing evidence is reported about in vitro and in vivo anti-angiogenic action of arginine deiminase from Mycoplasma spp.
E. A. Starikova +6 more
doaj +2 more sources
Regulation of Arginine-Ornithine Exchange and the Arginine Deiminase Pathway in Streptococcus lactis [PDF]
Streptococcus lactis metabolizes arginine by the argiqine deiminase (ADI) pathway. Resting cells of S. lactis grown in the presence of galactose and arginine maintain a high intracellular ornithine pool in the absence of arginine and other exogenous ...
DRIESSEN, AJM, POOLMAN, B, KONINGS, WN
core +9 more sources
Convergent evolution of the arginine deiminase pathway:the ArcD and ArcE arginine/ornithine exchangers [PDF]
The arginine deiminase (ADI) pathway converts L-arginine into L-ornithine and yields 1 mol of ATP per mol of L-arginine consumed. The L-arginine/L-ornithine exchanger in the pathway takes up L-arginine and excretes L-ornithine from the cytoplasm ...
Elke E. E. Noens +3 more
core +4 more sources
A protocol to induce systemic autophagy and increase energy metabolism in mice using PEGylated arginine deiminase [PDF]
Summary: Obesity is a prevalent metabolic disorder worldwide. Here, we describe a comprehensive protocol using pegylated arginine deiminase (ADI-EPG 20) to apply the concept that arginine depletion induces systemic autophagy to drive whole-body energy ...
Yiming Zhang, Brian J. DeBosch
doaj +2 more sources
Design and Production of Arginine Deiminase-Azurin Recombinant Fusion Protein from Pseudomonas aeruginosa and its Confirmation by Western Blot [PDF]
Background: Pseudomonas aeruginosa is a common Gram-negative, rod-shaped bacterium that has a unique genome that allowed the bacteria to produce various enzymes and proteins.
Mina Hadi +3 more
doaj +2 more sources

