Results 301 to 310 of about 63,662 (384)

ARL5B Drives Esophageal Squamous Cell Carcinoma Progression via ROCK1–SREBP1‐Mediated Lipid Metabolic Reprogramming

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Esophageal squamous cell carcinoma urgently requires new therapeutic strategies. Adenosine diphosphate‐ribosylation factor‐like protein 5B (ARL5B) is identified as a novel oncogene that remodels fatty acid metabolism through the ras homologous‐associated coiled‐coil containing protein kinase 1 (ROCK1)–sterol regulatory element‐binding protein 1 (SREBP1)
Xinyue Ma, Yanfei Sun, Hongyuan Mao, Chenhan Huang, Zerun Li, Tianzi Wang, Dizhi Jiang, Xinyu Zhang, Zhenyu Yuan, Zhihui Zhang, Bo Cheng, Ruiqing Wang, Yufeng Cheng   +12 more
wiley   +1 more source

Ovotoxicant VCD disrupts oocyte meiosis in mice by impairing m6A/IGF2BP3-mediated mRNA stability. [PDF]

Commun Biol
Li Y, Zhou Y, Liu J, Nie G, Cheng F, Yang H.   +5 more
europepmc   +1 more source

A Novel MPT‐Driven Necrosis‐Related lncRNA Signature for Prognostic Prediction in Hepatocellular Carcinoma: Validation Using Organoids

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Mitochondrial permeability transition (MPT)‐driven necrosis, a recently identified form of programmed cell death, significantly influences tumor progression, therapy response, and prognosis. However, research on mitochondrial permeability transition‐driven necrosis‐related long non‐coding ribonucleic acids (MPTDNRlncRNAs) in ...
Yang Liu, Liye Tao, Zefeng Shen, Junhao Zheng, Yali Wang, Meijie Chen, Yangyang Xie, Hongjun Chen, Jingwei Cai, Haoyu Pan, Shihao Li, Renan Jin, Junjie Xu, Xiao Liang   +13 more
wiley   +1 more source

Mechanistic Insights and Therapeutic Potential of Small Nucleolar RNA Host Genes in the Carcinogenesis of Hepatocellular Carcinoma

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Hepatocellular carcinoma (HCC) is one of the major factors endangering human health due to its poor prognosis, resulting from difficulties in early diagnosis and lack of effective treatment measures. Long non‐coding RNAs (lncRNAs), which are RNA molecules that do not translate into proteins, play essential roles in various tumor ...
Jiajia Luo, Zhangxiu Liao, Shuangxia Zhang   +2 more
wiley   +1 more source

Density-Dependent Expression of Epitranscriptomic, Stress and Appetite Regulating Genes in Atlantic Salmon. [PDF]

Mol Ecol
Frapin M, Quispe L, Troka J, Prokkola JM, Laurikainen O, Hyvärinen P, Primmer CR, Aykanat T, Ahi EP.   +8 more
europepmc   +1 more source

Pulsatile flow increases METTL14-induced m6A modification and attenuates septic cardiomyopathy: an experimental study

Shenyu Zhu, Kai Wang, Zhexuan Yu, Wei Tang, Yu Zhang, Shafiu A. Umar Shinge, Yongjia Qiang, Hangyu Liu, Jianfeng Zeng, Kun Qiao, Chi Liu, Guanhua Li   +11 more
openalex   +1 more source

Krüppel‐Like Factor 4, a Hub Gate for Cell Crosstalk in Tumor Microenvironment

Cancer Medicine, Volume 15, Issue 1, January 2026.
Krüppel‐like factor 4 (KLF4) exhibits a dual, context‐dependent role, acting as both a tumor suppressor and an oncogene. It remodels the tumor microenvironment by modulating cancer, stromal, and immune cells, representing a promising yet complex therapeutic target for cancer treatment.
Min Tang, Binle Tian, Jingyi Zhou, Di Ma, Rongze Sun, Qi Li   +5 more
wiley   +1 more source

Potyviruses recruit host eIF4A3 to block m6A-mediated RNA decay by steric hindrance of viral RNA methylation in plants. [PDF]

Nucleic Acids Res
Peng D, Dong L, Wang P, Zang L, Xie J, Wang H, Li X, Fan Z, Zhou T, Du K.   +9 more
europepmc   +1 more source