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Determinants of the m6A Epitranscriptome
2021N6–methyladenosine (m6A) is the most abundant mRNA modification and is crucial for gene expression regulation in numerous biological processes. In mammals, m6A methylation is specifically deposited on a subset of mRNAs and is strongly enriched within long internal exons and near stop codons.
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The Study of M6A epimodification regulating genes expression and m6A epimark level in human astrocytomas [PDF]
, 2020 Astrocytomas are astrocytes derived, diffusely infiltrating and the most frequent primary tumors in human brain. Astrocytomas according to tumor malignancy are classified into 4 grades of which the most common and aggressive are 4th grade tumors called glioblastomas (GBM) [1].
Samaitė, Katažyna +2 more
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m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer
Cancer Cell, 2020Huilin Huang, Jianjun Chen, Hengyou Weng
exaly
Hidden codes in mRNA: Control of gene expression by m6A
Molecular Cell, 2022Shino Murakami, Samie R. Jaffrey
exaly
m6A-RegBase enables regulatory investigation of m6A RNA modification in plants
Journal of Genetics and GenomicsBeilei Lei +11 more
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Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation
Cell, 2017Peng Jin +2 more
exaly
Spatially resolved m6A profiling using m6A-ARTR-DBiT
Nature MethodsYu Xiao +13 more
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