Results 201 to 210 of about 24,574 (283)
A prospective cohort study evaluating m6A RNA methylation in cutaneous squamous cell carcinoma [PDF]
Jake Lazaroff +7 more
openalex +1 more source
Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia +4 more
wiley +1 more source
Protein Lactylation in Cancer: Mechanisms and Therapeutic Targets
This schematic illustrates the central role of lactylation, a lactate‐derived posttranslational modification, in linking metabolic reprogramming to cancer progression and therapy resistance. At its core, lactylation modulates proteins, influenced by metabolic shifts and environmental factors.
Qianying Ouyang +10 more
wiley +1 more source
RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang +6 more
wiley +1 more source
The Role of One‐Carbon Metabolism in Cancer and Its Therapeutic Significance
One‐Carbon metabolism in T‐cell activation and tumor competition. T‐cell activation shifts metabolic pathways, promoting anabolic metabolism and bioenergetic capacity. One‐carbon metabolism plays a crucial role in histone and DNA methylation in activated T cells.
Yuting Jiang +3 more
wiley +1 more source
piRNA-14633 promotes cervical cancer cell malignancy in a METTL14-dependent m6A RNA methylation manner [PDF]
Qi Xie +10 more
openalex +1 more source
Fate by RNA methylation: m6A steers stem cell pluripotency [PDF]
Boxuan Zhao, Chuan He
core +1 more source
Select Small Non‐Coding RNAs Are Determinants of Survival in Older Adults
Circulating small RNAs were profiled by RNA sequencing in a well‐characterized cohort and evaluated alongside 187 clinical variables to predict survival. Models incorporating circulating small RNAs, including parsimonious subsets, outperformed age and clinical factors alone (AUC), with causal analyses supported by experimental evidence from the ...
Virginia Byers Kraus +12 more
wiley +1 more source
m6A RNA methylation modulates antiviral response in celiac disease. [PDF]
Sebastian-delaCruz M +11 more
europepmc +1 more source

