Results 41 to 50 of about 4,410 (162)

Availability of Cancer Screening Across HIV Treatment Sites in the IeDEA Consortium

International Journal of Cancer, Volume 159, Issue 6, Page 1477-1489, 15 September 2026.
In recent years, incorporating comprehensive cancer screening strategies into routine HIV care has gained growing attention. This survey of 220 sites providing HIV care across 41 countries shows that cervical cancer screening has increased in availability over time.
Rachael A. Pellegrino, Bryan E. Shepherd, Sanjay Pujari, Valeria Fink, Gad Murenzi, Miriam Nakalembe, Sally B. Coburn, Eliane Rohner, Antoine Jaquet, Caroline Lade, Brenda Crabtree Ramirez, Kathryn Anastos, Aggrey Semeere, Lesley S. Park, Limpho Mokone, Simon Boni, I Ketut Agus Somia, Emilia M. Jalil, Adebola Adedimeji, Omenge Orang'o, Michael J. Silverberg, Kumbirai Pise Quarter, Eugène Messou, Jeremy Ross, Eduardo Gotuzzo, Patricia Lelo, Helen Byakwaga, Oliver Ezechi, Jonathan Euvrard, Fernanda Maruri, Chad J. Achenbach, Jessica L. Castilho, on behalf of International epidemiology Databases to Evaluate AIDS (IeDEA)   +32 more
wiley   +1 more source

Assessment of Bone Mineral Density of Patients with Spinocerebellar Ataxia Type 3 [PDF]

Journal of Movement Disorders, 2019
Objective Machado-Joseph disease (MJD) is a spinocerebellar ataxia, and osteoporosis is a multifactor disease that may affect patients with neurologic conditions. The frequency of osteoporosis among MJD patients, however, has not been studied.
Aline MS Farias, Simone Appenzeller, Marcondes C França, Alberto RM Martinez, Elba E Etchebehere, Thiago F Souza, Allan O Santos   +6 more
doaj   +1 more source

Glutamate Dehydrogenase Deficiency in Machado-Joseph Disease [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1993
ABSTRACT:We studied the activity of glutamate dehydrogenase (GDH) in leukocytes from 23 patients with domi-nantly inherited ataxia. All the patients were assessed with a rating scale for ataxias and met the clinical criteria for the diagnosis of Machado-Joseph disease.
A, Gonçalves, C, Oliveira, M A, Ferro, M, Dinis, L, Cunha   +4 more
openaire   +2 more sources

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, Volume 13, Issue 7, Page 1370-1378, July 2026.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Machado-Joseph Disease: from first descriptions to new perspectives

Orphanet Journal of Rare Diseases, 2011
Machado-Joseph Disease (MJD), also known as spinocerebellar ataxia type 3 (SCA3), represents the most common form of SCA worldwide. MJD is an autosomal dominant neurodegenerative disorder of late onset, involving predominantly the cerebellar, pyramidal ...
Bettencourt Conceição, Lima Manuela
doaj   +1 more source

Muscle Excitability Abnormalities in Machado-Joseph Disease [PDF]

Archives of Neurology, 2008
To estimate the frequency of and to characterize muscle excitability abnormalities in Machado-Joseph disease (MJD).Machado-Joseph disease is a common autosomal dominant cerebellar ataxia caused by an unstable CAG trinucleotide repeat expansion. Muscle cramps and fasciculations are frequent and sometimes disabling manifestations.
Marcondes C, França, Anelyssa, D'Abreu, Anamarli, Nucci, Iscia, Lopes-Cendes   +3 more
openaire   +2 more sources

Generation of an induced pluripotent stem cell line (XHCSUi001-A) from urine cells of a patient with spinocerebellar ataxia type 3

Stem Cell Research, 2019
The induced pluripotent stem cell (iPSC) line XHCSUi001-A generated from urine cells of a female spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) patient by using the integration-free methods.
Lang He, Wei Ye, Zhao Chen, Chunrong Wang, Huifang Zhao, Shuai Li, Linliu Peng, Xiaobo Han, Tiancheng Zhou, Zhiyuan Li, Beisha Tang, Hong Jiang   +11 more
doaj   +1 more source

Two Decades of DNA Methylation Shifts Reveal Epigenomic Responses to Environmental Change in Wild Salmo salar From Its Southernmost Populations

Molecular Ecology, Volume 35, Issue 13, July 2026.
ABSTRACT Atlantic salmon (Salmo salar) populations have been declining across the North Atlantic, with southern populations, including those in rivers draining into the southwestern Bay of Biscay, showing some of the strongest impacts. These rivers mark the species' southernmost distribution limit and are highly vulnerable to global change stressors ...
Alvaro Gutierrez‐Rodriguez, Carmen Blanco‐Fernandez, Eva Garcia‐Vazquez, Gonzalo Machado‐Schiaffino   +3 more
wiley   +1 more source

Paula Coutinho’s outstanding contribution to the definition of Machado-Joseph disease

Arquivos de Neuro-Psiquiatria
Machado-Joseph disease, also known as spinocerebellar ataxia type 3, is the most common form of autosomal dominant ataxia in the world. Paula Coutinho, a highly-regarded Portuguese neurologist worldwide, had a seminal participation in the definition of ...
Bruno Carniatto Marques Garcia, Francisco Manoel Branco Germiniani, Paula Marques, Jorge Sequeiros, Hélio Afonso Ghizoni Teive   +4 more
doaj   +1 more source

Coenzyme Q10: Role in Less Common Age-Related Disorders

Antioxidants, 2022
In this article we have reviewed the potential role of coenzyme Q10 (CoQ10) in the pathogenesis and treatment of a number of less common age-related disorders, for many of which effective therapies are not currently available. For most of these disorders,
David Mantle, Iain P. Hargreaves
doaj   +1 more source