Results 91 to 100 of about 3,540,419 (389)

Compensation of a ball end tool trajectory in complex surface milling [PDF]

open access: yes, 2012
This work is consecrated to the minimising of machining errors based on a method for the compensation of the trajectory to be machined in hemispherical milling.
Baili, Maher   +4 more
core   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

The Effects of Alloy Composition and Surface Integrity on the Machinability of Austenitic Stainless Steels 304 and 304L

open access: yesJournal of Manufacturing and Materials Processing
Austenitic stainless steels, such as 304 and 304L, are extensively utilized in diverse industries due to their favorable properties, including biocompatibility, high durability, ductility, toughness at cryogenic temperatures, and excellent corrosion ...
Bahman Azarhoushang   +3 more
doaj   +1 more source

Technological characteristics of 245 tropical and temperate timbers species [PDF]

open access: yes, 2012
Developed by the Cirad's "Mediterranean and Tropical Forest Products Research Unit", the new release of TROPIX software (version 7) presents the main characteristics of 245 tropical or temperate wood species.
Beauchêne, Jacques   +14 more
core  

Experimental Characterization of Electrical Discharge Machining of Aluminum 6061 T6 Alloy using Different Dielectrics [PDF]

open access: yes, 2019
Electrical discharge machining is a non-traditional machining method broadly employed in industries for machining of parts that have typical profiles and require great accuracy.
Ismail, S. O.   +4 more
core   +4 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Multi-response optimization of CuZn39Pb3 brass alloy turning by implementing Grey Wolf algorithm

open access: yesFracture and Structural Integrity, 2019
Machinability of engineering materials is crucial for industrial manufacturing processes since it affects all the essential aspects involved, e.g. workload, resources, surface integrity and part quality. Two basic machinability parameters are the surface
Nikolaos Fountas   +3 more
doaj   +1 more source

Development of structural test articles from magnesium-lithium and beryllium [PDF]

open access: yes, 1969
Study on the fabrication and testing of a magnesium-lithium box beam shows the formability and machinability characteristics of that alloy to be excellent.
Alario, R.
core   +1 more source

Generalized bioinspired approach to a daytime radiative cooling "skin"

open access: yes, 2020
Energy-saving cooling materials with strong operability are desirable towards sustainable thermal management. Inspired by the cooperative thermo-optical effect in fur of polar bear, we develop a flexible and reusable cooling skin via laminating a ...
Guo, Jing   +9 more
core   +1 more source

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