Results 71 to 80 of about 28,059 (290)
Journal of Manufacturing and Materials ProcessingAustenitic stainless steels, such as 304 and 304L, are extensively utilized in diverse industries due to their favorable properties, including biocompatibility, high durability, ductility, toughness at cryogenic temperatures, and excellent corrosion ...
Bahman Azarhoushang +3 more
doaj +1 more source
A Comparative Study on Cutting Tool Performance in High-Speed Face-Milling of Hardened Tool Steels [PDF]
Archives of Metallurgy and MaterialsIn this study cutting speeds and tool life constants for seven different cutting tools are investigated while high-speed face milling of four different much used hardened tool steels.1.2379 and 1.2080 cold-work tool steels, 1.2344 hot-work tool steel and
Ali O. Er, E. Aslan
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Machine Learned Learning Machines
, 2017 There are two common approaches for optimizing the performance of a machine: genetic algorithms and machine learning. A genetic algorithm is applied over many generations whereas machine learning works by applying feedback until the system meets a performance threshold. Though these are methods that typically operate separately, we combine evolutionary
Sheneman, Leigh, Hintze, Arend
openaire +2 more sources
Technological characteristics of 245 tropical and temperate timbers species [PDF]
, 2012 Developed by the Cirad's "Mediterranean and Tropical Forest Products Research Unit", the new release of TROPIX software (version 7) presents the main characteristics of 245 tropical or temperate wood species.
Beauchêne, Jacques +14 more
core
Toolpath dependent stability lobes for the milling of thin-walled parts [PDF]
, 2008 The milling of thin-walled parts can become a seriously complex problem because the parts have variable dynamics. Firstly, the dynamics evolution of the part has been calculated through Finite Element Method (FEM) analysis.
Aramendi, Gorka +5 more
core +3 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Tool Life of PM-HSS Cutting Tools when Milling of Titanium Alloy [PDF]
, 2017 Machining of titanium alloys meets with poor life of a cutting tool. It is caused by a low thermal conductivity and by a high strength-to-weight ratio of the alloys. Various approaches for cost-effective and productive machining titanium alloys are still
Bach P., Trmal G., Zeman P.
core
Superplastic behaviour of Ti54M and Ti64 [PDF]
, 2020 Even though TIMETAL-54M (Ti-5Al-4V-0.6Mo-0.4Fe or Ti54M) has been commercially available for over 10 years, further study of its superplastic properties is still required in order to assess its applicability within the aerospace industry as a potential ...
Blackwell, Paul +4 more
core +4 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source