Results 91 to 100 of about 3,609,102 (305)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

On the feasibility of monitoring DTN: Impacts of fine tuning on routing protocols and the user experience [PDF]

, 2012
The “machine to machine” communication paradigm will become a central element for mobile networks. This paradigm can be easily constructed by a contact-based network, notably a disruption/delay tolerant networks (DTN).
Lochin, Emmanuel, Rakotoarivelo, Thierry, Ramiro, Victor, Sénac, Patrick   +3 more
core  

Capacity of Gaussian Many-Access Channels

, 2017
Classical multiuser information theory studies the fundamental limits of models with a fixed (often small) number of users as the coding blocklength goes to infinity.
Chen, Tsung-Yi, Chen, Xu, Guo, Dongning
core   +1 more source

The role of artificial intelligence in pandemic responses: from epidemiological modeling to vaccine development

Molecular Biomedicine
Integrating Artificial Intelligence (AI) across numerous disciplines has transformed the worldwide landscape of pandemic response. This review investigates the multidimensional role of AI in the pandemic, which arises as a global health crisis, and its ...
Mayur Suresh Gawande, Nikita Zade, Praveen Kumar, Swapnil Gundewar, Induni Nayodhara Weerarathna, Prateek Verma   +5 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Waveform Optimization for Large-Scale Multi-Antenna Multi-Sine Wireless Power Transfer

, 2016
Wireless power transfer (WPT) is expected to be a technology reshaping the landscape of low-power applications such as the Internet of Things, machine-to-machine communications and radio frequency identification networks.
Clerckx, Bruno, Huang, Yang
core   +1 more source

An enhanced light weight face liveness detection method using deep convolutional neural network

MethodsX
Authentication plays a pivotal role in contemporary security frameworks, with various methods utilized including passwords, hardware tokens, and biometrics.
Swapnil R. Shinde, Anupkumar M. Bongale, Deepak Dharrao, Sudeep D. Thepade   +3 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

A Survey of Random Access Control Techniques for Machine-to-Machine Communications in LTE/LTE-A Networks

IEEE Access, 2018
Machine-to-machine (M2M) communications refer to the autonomous interaction between connected devices without the human intervention. Recently, the Third-Generation Partnership Project (3GPP) introduced the Long-Term Evolution (LTE) and Long-Term ...
Huda Althumali, Mohamed Othman
doaj   +1 more source

Physics-informed machine learning

Nature Reviews Physics, 2021
G. Karniadakis, I. Kevrekidis, Lu Lu, P. Perdikaris, Sifan Wang, Liu Yang   +5 more
semanticscholar   +1 more source