Results 71 to 80 of about 5,351,341 (268)

Hilbert's machine and the Axiom of Infinity [PDF]

open access: yes, 2006
Hilbert's machine is a supertask machine inspired by Hilbert's Hotel whose functioning leads to a contradiction that compromises the Axiom of ...
Leon, Antonio
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Optimization of Loader Cabin

open access: yesTransactions of the VŠB-Technical University of Ostrava, Mechanical Series, 2011
Difficult operating conditions at mining put high demands on technical responsibility of mechanical machines and influence the operator of mechanical machines in a negative way as well.
Jan BLATA   +3 more
doaj   +1 more source

Diagnostics of Rotor Damages of Three-Phase Induction Motors Using Acoustic Signals and SMOFS-20-EXPANDED

open access: yesArchives of Acoustics, 2016
A fault diagnostics system of three-phase induction motors was implemented. The implemented system was based on acoustic signals of three-phase induction motors.
Adam GLOWACZ
doaj   +1 more source

Machine Learned Learning Machines

open access: yes, 2017
There are two common approaches for optimizing the performance of a machine: genetic algorithms and machine learning. A genetic algorithm is applied over many generations whereas machine learning works by applying feedback until the system meets a performance threshold. Though these are methods that typically operate separately, we combine evolutionary
Sheneman, Leigh, Hintze, Arend
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Turing Machine on the Dissecting Table [PDF]

open access: yes, 2013
Since the beginning of the twenty-first century there has been an increasing awareness that software rep- resents a blind spot in new media theory. The growing interest in software also influences the argument in this paper, which sets out from the ...
Horáková, Jana
core  

Quantum Cloning, Bell's Inequality and Teleportation

open access: yes, 2008
We analyze a possibility of using the two qubit output state from Buzek-Hillery quantum copying machine (not necessarily universal quantum cloning machine) as a teleportation channel. We show that there is a range of values of the machine parameter $\xi$
Adhikari, S.   +3 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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