Results 51 to 60 of about 2,769,211 (350)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Otonom Dozer için Küreme Algoritması Geliştirilmesi

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2018
Bu çalışmada insan müdahalesi olmadan küreme işleminingerçekleştirilebilmesi için yeni bir küreme algoritması geliştirilmiştir.Algoritmaya uygun biçimde küreme ve tesviye işlemlerini gerçekleştirmesi içinküçük ölçekli bir otonom iş makinesinin yapması ...
Adem Yıldırım, Önder Halis Bettemir
doaj   +1 more source

Вільна система ЧПУ для верстата паралельної структури [PDF]

, 2013
Application of LinuxCNC (open-source Linux based CNC software) to control parallel kinematic machine tools is considered. A control architecture and configuration files developed for LinuxCNC parallel kinematics machine tool with Stewart platform ...
Kyrychenko, A., Кириченко, А. М.   +1 more
core  

Machine Learning for Fluid Mechanics

, 2020
The field of fluid mechanics is rapidly advancing, driven by unprecedented volumes of data from field measurements, experiments and large-scale simulations at multiple spatiotemporal scales.
Brunton, Steven, Koumoutsakos, Petros, Noack, Bernd   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Crop leaf disease detection with additive gated convolution and hierarchical attention fusion

Scientific Reports
Crop leaf disease detection plays a crucial role in ensuring healthy crop growth and improving food security. Disease features are often small and have blurry edges, while background interference is strong, making precise detection a significant ...
Jing Liu, Xiaoyong Liu, Junjie Tao, Yanyan Cao, Xiaobo Zhou, Chaoping Guo, Chunyu Dong   +6 more
doaj   +1 more source

Universal and Automated Approaches for Optimising the Processing Order of Geometries in a CAM Tool for Redundant Galvanometer Scanner-Based Systems

Automation
The combination of highly dynamic systems with a limited work envelope with a less dynamic system with a larger working envelope promises to combine the advantages of both systems while eliminating the disadvantages.
Daniel Kurth, Colin Reiff, Yujiao Jiang, Alexander Verl   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Multi path attention and scale aware fusion for accurate object detection in remote sensing imagery

Scientific Reports
The pursuit of accurate yet computationally efficient object detection within remote sensing imagery remains a cornerstone for the advancement of intelligent interpretation systems.
Jing Liu, Junjie Tao, Xiaoyong Liu, Jun Ma, Chaoping Guo, Chunyu Dong, Pan Li, Peijun Shi   +7 more
doaj   +1 more source

Data validation: a case study for a feed-drive monitoring [PDF]

, 1999
The monitoring of machine-tools implicated in the metal cutting process is the subject of increasing developments because of requests on control, reliability, availability of machine-tools and on work-piece quality.
Desforges, Xavier, Habbadi, Abdallah, Noyes, Daniel   +2 more
core