Results 91 to 100 of about 1,297,449 (284)

Supervised learning with quantum enhanced feature spaces

open access: yes, 2018
Machine learning and quantum computing are two technologies each with the potential for altering how computation is performed to address previously untenable problems.
Chow, Jerry M.   +6 more
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

An analysis of question processing of English and Chinese for the NTCIR 5 cross-language question answering task [PDF]

open access: yes, 2005
An important element in question answering systems is the analysis and interpretation of questions. Using the NTCIR 5 Cross-Language Question Answering (CLQA) question test set we demonstrate that the accuracy of deep question analysis is dependent on ...
Guo, Yuqing   +3 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Investigation of the Machining Stability of a Milling Machine with Hybrid Guideway Systems

open access: yesApplied Sciences, 2016
This study was aimed to investigate the machining stability of a horizontal milling machine with hybrid guideway systems by finite element method. To this purpose, we first created finite element model of the milling machine with the introduction of the ...
Jui-Pin Hung   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparative analysis of salient pole and flux barrier rotor for synchronous reluctance machines including flux weakening range

open access: yesThe Journal of Engineering, 2019
Here, synchronous reluctance machine types related to electrical traction applications are investigated including flux weakening range. A flux barrier (FB) machine with a carbon fibre-reinforced plastic bandage and a salient pole machine are designed by ...
Matthias Hofer   +3 more
doaj   +1 more source

BLITZEN: A highly integrated massively parallel machine [PDF]

open access: yes
The architecture and VLSI design of a new massively parallel processing array chip are described. The BLITZEN processing element array chip, which contains 1.1 million transistors, serves as the basis for a highly integrated, miniaturized, high ...
Blevins, D. W.   +3 more
core   +1 more source

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