Results 41 to 50 of about 1,297,449 (284)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Influence of misalignment fluctuation on transmission error of planetary gears

Nihon Kikai Gakkai ronbunshu, 2014
The influence of the complicated behavior of the components of a planetary gearset (i.e., sun gear, carrier and ring gear) on transmission error is still unexplained.
Kouji KUMAGAI, Kunihiko MORIKAWA, Mikio NAGAHARA, Masaharu KOMORI   +3 more
doaj   +1 more source

Machine learning and physical based modeling for cardiac hypertrophy

Heliyon, 2023
Background and objective: Predicting the long-term expansion and remodeling of the left ventricle in patients is challenging task but it has the potential to be clinically very useful.
Bogdan Milićević, Miljan Milošević, Vladimir Simić, Andrej Preveden, Lazar Velicki, Đorđe Jakovljević, Zoran Bosnić, Matej Pičulin, Bojan Žunkovič, Miloš Kojić, Nenad Filipović   +10 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Design and finite element mode analysis of noncircular gear [PDF]

, 2008
The noncircular gear transmission is an important branch of the gear transmission, it is characterized by its compact structure, good dynamic equilibration and other advantages, and can be used in the automobile, engineering machine, ship, machine tool ...
Cheng, K, Lin, C, Qin, D, Qiu, H, Ran, X, Zhu, C   +5 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Simulation of Rolling Contact Fatigue Strength for Traction Drive Elements

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2013
A simulation of the rolling contact fatigue strength of a traction drive element was proposed. The simulation can account for both the distribution of sizes of inclusions in the element material and the influence of traction forces at the element surface.
Yukihito NARITA, Masashi YAMANAKA, Toshiharu KAZAMA, Yasuhiro OSAFUNE, Tomoya MASUYAMA   +4 more
doaj   +1 more source

Predetermination of Currents and Field in Short-Circuit Voltage Operation for an Axial-Flux Permanent Magnet Machine [PDF]

, 2008
Risk of irreversible magnet demagnetization during short-circuit fault is analyzed in case of an axial-flux dual-rotor machine, using a three-dimensional finite-element method (3D-FEM).
HENNERON, Thomas, LOCMENT, Fabrice, PIRIOU, Francis, SEMAIL, Eric   +3 more
core   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Effect of crowning radius on rolling contact fatigue strength for traction drive elements (Evaluation by simulation)

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2014
A simulation of the rolling contact fatigue strength of a traction drive element was developed. This simulation accounts for both the distribution of sizes of inclusions in the element material and the influence of traction forces at the element surface.
Yukihito NARITA, Naoto KATO, Masashi YAMANAKA, Toshiharu KAZAMA, Yasuhiro OSAFUNE, Tomoya MASUYAMA   +5 more
doaj   +1 more source