Results 81 to 90 of about 1,297,449 (284)

The finite element machine: An experiment in parallel processing [PDF]

open access: yes
The finite element machine is a prototype computer designed to support parallel solutions to structural analysis problems. The hardware architecture and support software for the machine, initial solution algorithms and test applications, and preliminary ...
Adams, L.   +4 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Layered Thin Film Micro Parts Reinforced with Aligned Short Fibers in Laser Stereolithography by Applying Magnetic Field

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
The purpose of this research is to produce micro parts reinforced by unidirectional short fibers using laser stereolithography. Ferromagnetic short fibers are added to a liquid photopolymer and a magnetic field is then applied to the liquid photopolymer,
Takeshi NAKAMOTO, Shinya KOJIMA
doaj   +1 more source

Advanced nonlinear modelling techniques for switched reluctance machines [PDF]

open access: yes, 2003
This paper gives an overview of different modelling techniques to describe the nonlinear behaviour of both saturated switched reluctance machine (SRM) and power electronic converter.
Belmans, Ronnie   +3 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Whisker Alignment in Microparts Using Laser Stereolithography with Applied Electric Field

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2013
The purpose of this research is to produce microparts reinforced with unidirectional whiskers using laser stereolithography. Electrically conductive whiskers are added to a liquid photopolymer and an electric field is applied to the liquid photopolymer ...
Takeshi NAKAMOTO   +2 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Effect of internal clearance on rolling element load of double row tapered roller bearings

open access: yesNihon Kikai Gakkai ronbunshu, 2016
An external load applied to a rolling bearing is distributed among the rolling elements. This rolling element load distribution is changed according to the way the external load is applied or the internal clearance of the bearing. And, it will affect the
Ken TAKAHASHI   +2 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

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