Results 101 to 110 of about 8,730,293 (397)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

A Closure Contact Model of Self-Affine Rough Surfaces Considering Small-, Meso-, and Large-Scale Stage Without Adhesive

Fractal and Fractional
Contact interface is essential for the dynamic response of the bolted structures. To accurately predict the dynamic characteristics of bolted joint structures, a fractal extension of the segmented scale model, i.e., the JK model, is proposed in this ...
Tao Zhang, Yiming Wu, Xian Liu, Kai Jiang   +3 more
doaj   +1 more source

Weld preparation tool for pipes and tubing [PDF]

, 1968
Improved scarfing tool consists of a mount-table, roller-guided assembly.
Wallace, E. D.
core   +1 more source

Dynamic Accuracy Design Method of Ultra-precision Machine Tool

, 2018
Ultra-precision machine tool is the most important physical tool to machining the workpiece with the frequency domain error requirement, in the design process of which the dynamic accuracy design (DAD) is indispensable and the related research is rarely ...
Guoda Chen, Yazhou Sun, Fei-hu Zhang, Li-hua Lu, Wanqun Chen, Nan Yu   +5 more
semanticscholar   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Design and manufacture of testing measurement and evaluation device for dynamic property of metallic interfaces

Nihon Kikai Gakkai ronbunshu, 2015
Metallic interfaces in mechanical structures cause dynamic damping property. It is very effective to apply this good damping property to engine power plant in order to reduce noise and vibration, however, it is difficult to use dynamic damping property ...
Kenichi YAMASHITA, Shinji SHIMIZU, Haruhisa SAKAMOTO   +2 more
doaj   +1 more source

Вільна система ЧПУ для верстата паралельної структури [PDF]

, 2013
Application of LinuxCNC (open-source Linux based CNC software) to control parallel kinematic machine tools is considered. A control architecture and configuration files developed for LinuxCNC parallel kinematics machine tool with Stewart platform ...
Kyrychenko, A., Кириченко, А. М.   +1 more
core  

Evaluation of servo, geometric and dynamic error sources on five axis high-speed machine tool

, 2011
Many sources of errors exist in the manufacturing process of complex shapes. Some approximations occur at each step from the design geometry to the machined part.
Andolfatto, Loïc, Lavernhe, Sylvain, Mayer, René   +2 more
core   +2 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Effect of pulse frequency on microstructure and properties of laser additive manufactured Inconel 718

Journal of Materials Research and Technology
Laser additive manufacturing of Inconel 718 nickel-based superalloy (In718) typically results in coarse columnar grains, which adversely affect its mechanical properties.
Yuanjun Su, Jingjie Zhang, Guangchun Xiao, Hui Chen, Mingdong Yi, Zhaoqiang Chen, Hui Zhang, Chonghai Xu   +7 more
doaj   +1 more source