Results 11 to 20 of about 1,789,694 (253)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Reactive Atom Plasma (RAP) figuring machine for meter class optical surfaces [PDF]
, 2013 A new surface figuring machine called Helios 1200 is presented in this paper. It is designed for the figuring of meter sized optical surfaces with form accuracy correction capability better than 20 nm rms within a reduced number of iterations.
Castelli, Marco +4 more
core +1 more source
Machining stability and machine tool dynamics [PDF]
, 2007 Machining is a common manufacturing process in industry due to its high flexibility and ability to produce parts which excellent quality. The productivity and quality in machining operations can be limited by several process constraints one of which is ...
Budak, Erhan
core
Tilted Tool Axis Machining on 5-Axis Machine Tools
International Journal of Automation Technology, 2007 High-efficiency machining and high-quality cutting are required in mold and die machining. To produce high-quality molds and dies, we require high rigidity for cutting tools and machining with effective cutting edges. We propose tilted tool axis machining, which involves indexing using 2-axis rotary motion and machining using 3-axis feed motion on ...
Makoto Yamada +3 more
openaire +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Optical machine tool alignment indicator Patent [PDF]
, 1971 Optical gauging system for monitoring machine tool ...
Boissevain, A. G., Nelson, B. W.
core +1 more source
Cyber-physical Machine Tool – The Era of Machine Tool 4.0
Procedia CIRP, 2017 In the past five years, several industrial initiatives such as “Industry 4.0”, “Industrial Internet of Things”, “Factories of the Future” and “Made in China 2025”, have been announced by different governments and industrial leaders. These initiatives lead to an urgent need to advance current manufacturing systems into a high level of intelligence and ...
Liu, Chao, Xu, Xun
openaire +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Innovative Service-Based Business Concepts for the Machine Tool Building Industry [PDF]
, 2009 Organised by: Cranfield UniversityDuring the last decade, machine tool building companies have been forced to put innovative offers on the market. Due to the technical features of their products and the prevailing organizational structures in this ...
Biege, S. +4 more
core