Results 31 to 40 of about 377,457 (261)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Advances in Mechanical Engineering, 2016 A new spindle’s axial thermal growth model based on temperature variation is proposed considering the limitations of spindle’s axial thermal growth model based on rotating speed.
Kuo Liu +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Effects of Cooling Systems on the Thermal Behaviour of Machine Tools and Thermal Error Models
Journal of Machine Engineering, 2020 Today, cooling systems are increasingly applied to the structure of machine tools (MT). Unfortunately, to date there have been few efforts to precisely control these cooling systems, which inhibits the full utilisation of their potential to improve MT ...
Martin Mareš +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Tangential mechanical properties analysis of cylindric elastoplastic contact model
Advances in Mechanical Engineering, 2022 An elastoplastic contact model of two cylinders is proposed in this paper. The crossing angle of two cylinders axes is introduced into the contact model.
Tieneng Guo +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Scientific ReportsGear skiving is an efficient and precise method for gear manufacturing. Traditional conical skiving tools feature a structural relief angle on the flank and a plane rake face, which often leads to inconsistent accuracy after regrinding and an ...
Jiaxue Ji +5 more
doaj +1 more source
Journal of Manufacturing and Materials Processing, 2020 During the milling of thin-walled workpieces, the natural frequencies might change radically due to the material removal. To avoid resonant spindle speeds and chatter vibration, a precise knowledge of the instantaneous modal parameters is necessary. Many
Daniel Bachrathy +5 more
doaj +1 more source