Results 51 to 60 of about 5,306,001 (276)
Tangential mechanical properties analysis of cylindric elastoplastic contact model
An elastoplastic contact model of two cylinders is proposed in this paper. The crossing angle of two cylinders axes is introduced into the contact model.
Tieneng Guo +4 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Tool Wear in Milling of Medical Grade Cobalt Chromium Alloy - Requirements for Advanced Process Monitoring and Data Analytics [PDF]
The Machine Tool Technologies Research Foundation (MTTRF) and iAM-CNC Annual Meeting 2016, San Fransisco, California, USA, 5-7 July 2016Computer Aided Design (CAD), Computer Aided Manufacturing (CAM) and Computer Numerical Control (CNC) are platform ...
Ahearne, Eamonn +4 more
core +1 more source
During the milling of thin-walled workpieces, the natural frequencies might change radically due to the material removal. To avoid resonant spindle speeds and chatter vibration, a precise knowledge of the instantaneous modal parameters is necessary. Many
Daniel Bachrathy +5 more
doaj +1 more source
There is inevitably an angular offset during contact of mechanical structures such as roller bearings or gears. Most of the previous contact models involve the contact between two parallel cylinders.
Tieneng Guo, Ruguo Ji, Yunfei Ma
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Modeling and Error Compensation for Concentric Grinding of Spherical Surfaces
To improve the form accuracy of spherical surfaces generated by cup-wheel grinding, this paper presents a geometric modeling and error compensation method for concentric grinding of spherical surfaces.
Baozhen Li +4 more
doaj +1 more source
Automatic planning for machine tool calibration: A case study [PDF]
Machine tool owners require knowledge of their machine’s capabilities, and the emphasis increases with areas of high accuracy manufacturing. An aspect of a machine’s capability is its geometric accuracy. International Standards and best-practice guides
P. Gregory +13 more
core +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source

