Results 71 to 80 of about 1,787,073 (298)
Springback Prediction of Dieless Forming of AZM120 Sheet Metal Based on Constitutive Model
Metals, 2020 Springback control is a key issue of the sheet-metal-forming process. In this paper, the mechanism of sheet-metal-forming along the folding trajectory of the computer numerical control (CNC) four-side automatic panel bender was studied, based on the bend-
Zijin Wu +5 more
doaj +1 more source
Data validation: a case study for a feed-drive monitoring [PDF]
, 1999 The monitoring of machine-tools implicated in the metal cutting process is the subject of increasing developments because of requests on control, reliability, availability of machine-tools and on work-piece quality.
Desforges, Xavier +2 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
MathematicsUnpredictable sudden disturbances such as machine failure, processing time lag, and order changes increase the deviation between actual production and the planned schedule, seriously affecting production efficiency. This phenomenon is particularly severe
Jun Yan +5 more
doaj +1 more source
Advances in Mechanical Engineering, 2019 Analyzing of nonlinear carrying performance of hydrostatic ram is among key research questions to improve heavy machine tools because the machining precision will be directly influenced by it.
Yumo Wang +5 more
doaj +1 more source
Optical alignment of electrodes on electrical discharge machines [PDF]
, 1972 Shadowgraph system projects magnified image on screen so that alignment of small electrodes mounted on electrical discharge machines can be corrected and verified.
Boissevain, A. G., Nelson, B. W.
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
A Preliminary Study of Applying Lean Six Sigma Methods to Machine Tool Measurement [PDF]
, 2015 Many manufacturers aim to increase their levels of high-quality production in order to improve their market competitiveness. Continuous improvement of maintenance strategies is a key factor to be capable of delivering high quality products and services ...
Fletcher, Simon +2 more
core