Results 71 to 80 of about 7,726,210 (354)

Classification of drilling surface roughness on computer numerical control (CNC) machine tools based on Mobilenet_v3_small_improved [PDF]

Mechanical Sciences
Computer numerical control (CNC) machine tool drilling is a crucial process in the contemporary manufacturing sector, facilitating high-precision fabrication of complex components and thus enhancing production efficiency and product quality.
G. Chen, W. Peng, J. Tu, W. Wang, H. Zhao   +4 more
doaj   +1 more source

An integrated decision-making method for selecting machine tool guideways considering remanufacturability

International journal of computer integrated manufacturing (Print), 2018
As one of the most important components of machine tool, guideway has an important driving force to comprehensively improve the remanufacturability of machine tools.
Zhouyang Ding, Zhigang Jiang, Hua Zhang, Wei Cai, Y. Liu   +4 more
semanticscholar   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

A systematic study on the dynamic recrystallization behavior of S55C during hot deformation

Journal of Materials Research and Technology
The hot deformation behavior of S55C steel was systematically investigated via isothermal compression tests over a temperature range of 850–1000 °C and a strain rate range of 0.01–10 s−1.
Wenshuai Yan, Qingle Hao, Yuting Zhou, Junhui Song, Kaipeng Zhao, Weimin Long   +5 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

A Closure Contact Model of Self-Affine Rough Surfaces Considering Small-, Meso-, and Large-Scale Stage Without Adhesive

Fractal and Fractional
Contact interface is essential for the dynamic response of the bolted structures. To accurately predict the dynamic characteristics of bolted joint structures, a fractal extension of the segmented scale model, i.e., the JK model, is proposed in this ...
Tao Zhang, Yiming Wu, Xian Liu, Kai Jiang   +3 more
doaj   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

CAD/CAM System for Insole Production

Communications, 2000
Impressive strides in medicine enhanced a necessity for highly advanced computer systems which would provide measurement and visualization aids with a high degree of accuracy, and high standards for planning and application of specific medical procedures.
Toma Udiljak, Karlo Obrovac, Igor Ištef
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source