Results 81 to 90 of about 1,787,073 (298)

Analytical and experimental study of feed rate in high-speed milling [PDF]

open access: yes, 2013
In the context of high-speed milling (HSM), during the machining process dynamic machine response has to be identified. To achieve this, we have to calculate the feed rate evolution in linear and circular interpolation according to dynamic performance of
Baili, Maher   +4 more
core   +3 more sources

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Design of an electrochemical micromachining machine [PDF]

open access: yes, 2014
Electrochemical micromachining (μECM) is a non-conventional machining process based on the phenomenon of electrolysis. μECM became an attractive area of research due to the fact that this process does not create any defective layer after machining and ...
A Muetze   +40 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Optical machine tool alignment indicator Patent [PDF]

open access: yes, 1971
Optical gauging system for monitoring machine tool ...
Boissevain, A. G., Nelson, B. W.
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Application of Mineral Casting for Machine Tools Beds. [PDF]

open access: yes, 2013
The article provides state of the art and the latest development trends in the manufacturing of machine tool beds. The emphasis is placed on modern materials whose mechanical and dynamical properties may prove to be a breakthrough in the field of machine
Kępczak, Norbert, Pawłowski, Witold
core  

Macroscopic simulation of the liner honing process [PDF]

open access: yes, 2012
The form quality, the roughness and the surface appearance produced by honing minimizes the friction of the piston in the liner. The process is however mechanically complex and the selection of the process parameters is currently based on empirical ...
DUMUR, Didier   +2 more
core   +5 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Weld preparation tool for pipes and tubing [PDF]

open access: yes, 1968
Improved scarfing tool consists of a mount-table, roller-guided assembly.
Wallace, E. D.
core   +1 more source

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