Results 51 to 60 of about 326,112 (261)

Investigation of Tool Cooling and Heat Transfer Using Computational Fluid Dynamics Simulations

Journal of Machine Engineering
Thermal errors remain one of the biggest challenges for the precision of cutting machine tools. Aside from optimizations in the machine tool design and behaviour, optimal cutting process parameters and targeted usage of cutting fluid or alternative ...
Christian Naumann, Claus-Dieter Schmidt, Alexander Geist, Steffen Brier, Janine Glanzel, Philipp Klimant, Steffen Ihlenfeldt, Martin Dix   +7 more
doaj   +1 more source

Guarding Machine Tools [PDF]

Proceedings of the Institution of Mechanical Engineers, 1902
n ...
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Concept of Integrating a Hybrid Thermal Error Compensation Into an Existing Machine Tool Control Architecture

Journal of Machine Engineering
Thermal error compensation via a numeric control (NC) system is a proven option for upgrading the precision of machine tools. The main advantage is the generally cost-effective application, as no changes to the machine design are necessary. Since modern
Alexander Geist, Muhammad Faisal Yaqoob, Christian Friedrich, Christian Naumann, Steffen Ihlenfeldt   +4 more
doaj   +1 more source

Modelling of a Thermoelectric Self-Cooling System Based on Thermal Resistance Networks for Linear Direct Drives in Machine Tools

Journal of Machine Engineering, 2020
The use of direct drives in linear and rotary axes as well as increased power density of main drives offer the potential to raise feet rate, acceleration and thus allow higher productivity of machine tools.
Eckart UHLMANN, Sebastian SALEIN, Mitchel POLTE, Florian TRIEBEL   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Machine vision in manufacturing SMEs: a review

Discover Applied Sciences
Automating manufacturing tasks, such as quality control, fault detection, part classification, and inventory management with machine vision systems can significantly improve process efficiency, accuracy, and productivity.
Jonas Werheid, Hannes Behnen, Jan-Henrik Woltersmann, Shengjie He, Tobias Hamann, Anas Abdelrazeq, Robert H. Schmitt   +6 more
doaj   +1 more source

Predictive Technology Assessment by Means of a Structure-Based Method of Machine Learning

Journal of Machine Engineering, 2020
From a user perspective, the current development of the generic term Industry 4.0 increasingly moves its orientation towards flexible production. Due to increasingly variable products with small quantities and the resulting high degree of adaptability of
Manja Mai-Ly PFAFF, Uwe FRIEß, Andreas OTTO, Matthias PUTZ   +3 more
doaj   +1 more source

Investigation of the material separation behaviour of rocks using scratch tests for the design of tool grinding processes

SN Applied Sciences, 2022
Article Highlights Investigating material removal mechanisms of rocks against the background of tool grinding. Identifying optima of cutting speed and single grain chip thickness for ductile material removal for rocks.
Berend Denkena, Bernd Breidenstein, Benjamin Bergmann, Philipp Wolters   +3 more
doaj   +1 more source