Results 71 to 80 of about 8,584,927 (344)
Continuous generating grinding processes have largely replaced discontinuous profile grinding processes in gear manufacturing due to their higher productivity.
Berend Denkena +3 more
doaj +1 more source
Friction in the piston-cylinder system of combustion engines has a great influence on fuel consumption. To reduce the friction of combustion engines, free-form cylinder liners and microstructured cylinder liners have proven to be advantageous.
Berend Denkena +3 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
This paper presents sensor data integration and information fusion to build “digital-twins” virtual machine tools for cyber-physical manufacturing. Virtual machine tools are useful for simulating machine tools’ capabilities in a safe and cost-effective ...
Yi Cai +3 more
semanticscholar +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigation of Tool Cooling and Heat Transfer Using Computational Fluid Dynamics Simulations
Thermal errors remain one of the biggest challenges for the precision of cutting machine tools. Aside from optimizations in the machine tool design and behaviour, optimal cutting process parameters and targeted usage of cutting fluid or alternative ...
Christian Naumann +7 more
doaj +1 more source
In this paper, we use the blockchain technology to design a prototype to secure process data from a 3D-printer. Datastreams are gathered from various sources such as OPC UA servers and autonomous retrofit sensor nodes.
Gordon Lemme +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

