Results 81 to 90 of about 5,164,018 (286)

Opening of Production Engineering Machine Tools Laboratory, 1961 -- 06

, 1961
Opening of Production Engineering Machine Tools Laboratory, by O.E.
Swinburne Technical College
core  

Multi-agent framework based on smart sensors/actuators for machine tools control and monitoring [PDF]

, 2006
Throughout the history, the evolutions of the requirements for manufacturing equipments have depended on the changes in the customers' demands. Among the present trends in the requirements for new manufacturing equipments, there are more flexible and ...
Archimède, Bernard, Desforges, Xavier
core   +1 more source

The significance of air pockets for modelling thermal errors of machine tools [PDF]

, 2013
It is well known, especially with the prevalence of compensation for geometric errors, that thermal error represents the most significant proportion of the total volumetric error of the machine tool. Thermal error in machine tools originates from changes
Longstaff, Andrew P., Mian, Naeem S., Fletcher, Simon, Myers, Alan   +3 more
core   +2 more sources

Simulation of the structural elements of a three axis VMC for machine tool error compensation [PDF]

, 2008
Great interest is being made by manufacturers and end users in the reduction of inherent errors which occur in the design and manufacture of machine tools.
Longstaff, Andrew P., Barrans, Simon, Pislaru, Crinela, Fletcher, Simon, Poxton, Anthony, Myers, Alan   +5 more
core   +4 more sources

Influence of the Substrate Size on the Cooling Behavior and Properties of the DED-LB Process

Journal of Machine Engineering
The laser-based Directed Energy Deposition (DED-LB) process involves a complex thermal history which strongly de-pends on the geometry of the deposited structure and substrate.
Fabian Bieg, Clemens Maucher, Hans-Christian Möhring   +2 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Advanced Material Studies for Additive Manufacturing in terms of Future Gear Application

Advances in Mechanical Engineering, 2014
Additive manufacturing by laser beam melting is predestined for complex component geometry like integrated cooling channels without enormous posttreatment processing.
Jan Bräunig, Thomas Töppel, Bernhard Müller, Martin Burkhardt, Thomas Hipke, Welf-Guntram Drossel   +5 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source