Results 81 to 90 of about 1,714,603 (291)

Development of a Novel MultiBody Mechatronic Model for Five-Axis CNC Machine Tool [PDF]

open access: yes, 2015
The paper presents the development of a mechatronic hybrid model for Geiss five-axis CNC machine tool using MultiBody-System (MBS) approach. The motion control systems comprising electrical and mechanical elements are analyzed and modeled.
Papananias, M.   +2 more
core  

Study of energy deposition patterns in hadron calorimeter for prompt and displaced jets using convolutional neural network

open access: yes, 2019
Sophisticated machine learning techniques have promising potential in search for physics beyond Standard Model in Large Hadron Collider (LHC). Convolutional neural networks (CNN) can provide powerful tools for differentiating between patterns of ...
Bhattacherjee, Biplob   +2 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Machine tools and fixtures: A compilation [PDF]

open access: yes
Innovations developed by NASA, AEC, and their contractors concerning tools, adaptors, jigs, and fixtures useful in machining a wide variety of materials are ...

core   +1 more source

Comparison of Volumetric Analysis Methods for Machine Tools with Rotary Axes [PDF]

open access: yes, 2009
Confidence in the ability of a production machine to meet manufacturing tolerances requires a full understanding of the accuracy of the machine. However, the definition of “the accuracy of the machine” is open to interpretation. Historically, this has
Fletcher, Simon   +3 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Part Form Errors Predicted from Machine Tool Performance Measurements [PDF]

open access: yes, 1997
Machine tool performance testing, as defined by IS0 230 and ANSI B5.54 has been successfully used to maintain and improve the accuracy and repeatability of production-level machine tools.
Farabaugh, F.   +3 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Influence of the Substrate Size on the Cooling Behavior and Properties of the DED-LB Process

open access: yesJournal of Machine Engineering
The laser-based Directed Energy Deposition (DED-LB) process involves a complex thermal history which strongly de-pends on the geometry of the deposited structure and substrate.
Fabian Bieg   +2 more
doaj   +1 more source

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