Results 101 to 110 of about 3,785,147 (434)

A coiled‐coil domain triggers oligomerization of MmpL10, the mycobacterial transporter of trehalose polyphleate precursor

open access: yesFEBS Letters, EarlyView.
Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston   +7 more
wiley   +1 more source

Process simulation for 5-axis machining using generalized milling tool geometries [PDF]

open access: yes, 2010
Multi-axis machining (especially 5-axis machining) is widely used in precision machining for automotive, aerospace and die-mold manufacturing. The goal in precision machining is to increase production while meeting high part quality needs which can be ...
Budak, Erhan   +2 more
core  

Feedrate planning for machining with industrial six-axis robots [PDF]

open access: yes, 2010
The authors want to thank Stäubli for providing the necessary information of the controller, Dynalog for its contribution to the experimental validations and X.
BEAREE, Richard   +3 more
core   +5 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Cutting Performance of Different Coated Micro End Mills in Machining of Ti-6Al-4V

open access: yesMicromachines, 2018
Tool wear is a significant issue for the application of micro end mills. This can be significantly improved by coating materials on tool surfaces. This paper investigates the effects of different coating materials on tool wear in the micro milling of Ti ...
Zhiqiang Liang   +5 more
doaj   +1 more source

Lecture Notes: Optimization for Machine Learning [PDF]

open access: yesarXiv, 2019
Lecture notes on optimization for machine learning, derived from a course at Princeton University and tutorials given in MLSS, Buenos Aires, as well as Simons Foundation, Berkeley.
arxiv  

Towards Modular Machine Learning Solution Development: Benefits and Trade-offs [PDF]

open access: yesarXiv, 2023
Machine learning technologies have demonstrated immense capabilities in various domains. They play a key role in the success of modern businesses. However, adoption of machine learning technologies has a lot of untouched potential. Cost of developing custom machine learning solutions that solve unique business problems is a major inhibitor to far ...
arxiv  

Investigation on different composition of powder metallurgy electrode (Cu-W) in high performance edm (HPEDM) on AISI D2 hardened steel [PDF]

open access: yes, 2013
The ideal selection of manufacturing conditions is one of the most important aspects to take into consideration in the majority of manufacturing processes and particularly in processes related to Electrical Discharge Machining (EDM).
Abdul Hamid, Faizul Ezmat
core  

Chatter milling modeling of active magnetic bearing spindle in high-speed domain [PDF]

open access: yes, 2011
A new dynamical modeling of Active Magnetic Bearing Spindle (AMBS) to identify machining stability of High Speed Milling (HSM) is presented. This original modeling includes all the minimum required parameters for stability analysis of AMBS machining. The
Arnaud, Lionel   +2 more
core   +3 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

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