Results 51 to 60 of about 87,256 (241)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

TRANSIENT RESPONSE ANALYSIS OF MACHINING CENTER UNDER IMPACT OF HIGH ACCELERATION

Jixie qiangdu, 2018
The manufacturing processing of blade,which has complicated structure and irregular surface shape,become increasingly high-speed.Thus,high acceleration is required to ensure the rapid movement of each axis.At the same time,the machining accuracy should ...
MI Jie, ZHEN Zhen, ZHU YingPing
doaj  

On the stability of high-speed milling with spindle speed variation [PDF]

, 2010
Spindle speed variation is a well-known technique to suppress regenerative machine tool vibrations, but it is usually considered to be effective only for low spindle speeds.
BP Mann, E Al-Regib, E Budak, E Solis, F Yang, Gilles Dessein, Grégoire Peigné, GS Duncan, H Paris, H Zhang, J Tlusty, J Tlusty, JS Sexton, JS Sexton, JS Sexton, Lionel Arnaud, M Zatarain, MA Davies, ML Campomanes, ND Sims, PV Bayly, R Radulescu, RPH Faassen, S Jayaram, S Sastry, S Seguy, S Seguy, S Smith, SA Tobias, SC Lin, SD Merdol, Sébastien Seguy, T Insperger, T Insperger, T Insperger, T Insperger, T Surmann, T Takemura, Tamás Insperger, TC Tsao, XH Long, Y Altintas, Y Altintas, Y Altintas   +43 more
core   +4 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Research of Spiral Bevel Gear Tooth Surface Modification Technique based on Machining Center

Jixie chuandong, 2016
On the consideration of the existing tooth surface modification technology of spiral bevel gear limited to special milling tooth machine,a kind of tooth surface modification method based on the machining center is put forward.
Wang Lei, Cao Xuemei, Deng Xiaozhong, Lei Baozhen   +3 more
doaj  

Cooling of spindle shaft for machining center using heat exchangers

Journal of Advanced Mechanical Design, Systems, and Manufacturing
The cooling method for machining center spindles commonly involves utilizing a fixed-side jacket cooling system with lubricating oil or coolant as the refrigerant.
Shingo KAJIKAWA, Sho MORITA, Naohiko SUGITA   +2 more
doaj   +1 more source

Fabrication of magic-mirror with magnetic polishing and end-milling on machining center

Nihon Kikai Gakkai ronbunshu, 2014
Recently, with the fabrication of the magic-mirror having the micro C2-continuous surface, it is difficult to hand down magic-mirror fabrication technology, due to downsizing of veteran engineers or even their successors.
Tatsuya FURUKI, Lei MA, Toshiki HIROGAKI, Eiichi AOYAMA, Keiji OGAWA   +4 more
doaj   +1 more source

Analysis of cutting parameters in point machining of parts with complex shape [PDF]

, 2018
This paper presents developed SW module in the postprocessor, which is designed to backward analysis of CAM milling toolpath. The module is designed to analyze multi-axis finishing machining of complex shape parts with milling cutters with a circular ...
Rybín J., Stejskal M., Vavruška P., Zeman P.   +3 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Tool Path Generation for the Formation of a Geometric Surface Pattern on a Curved Surface by Patch Division Milling

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2008
A textural surface pattern is used to add a physical or decorative function to an object's surface. We have proposed a milling technique involving patch division that can quickly generate a geometric surface pattern using a common profile-forming ...
Hiroshi MATSUDA, Hiroyuki SASAHARA, Masaaki FUKUDA, Masaomi TSUTSUMI   +3 more
doaj   +1 more source