Results 101 to 110 of about 12,418 (275)

The Fight for the Middle: Upgrading, Competition, and Industrial Development in China [PDF]

open access: yes
When China acceded to WTO in 2001, there were fears that Chinese firms would lose market share in key sectors to foreign-invested enterprises (FIEs). Although aggregate data often indicate a shift in favour of FIEs, indigenous firms in many cases have ...
Eric Thun, Loren Brandt
core  

Reduction of the mesh size influence on the results of a lagrangian finite element machining mode [PDF]

open access: yes, 2017
Mesh dependence of the results of a finite element model are well known in many fields such as in structural design. This problem is however not much addressed in the literature for machining modelling although it is crucial for the quality of the results ...
Ducobu, François   +2 more
core  

Experimental study of the high strain rate shear behaviour of Ti6Al4V [PDF]

open access: yes, 2011
Three different high strain rate shear test techniques are applied on the titanium alloy Ti6Al4V. Two techniques for testing of bulk materials and one technique for sheet materials are used: torsion of thin-walled tubes, compression of hat-shaped ...
Degrieck, Joris   +2 more
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Yield stress distribution in injection-mouldedglassy polymers [PDF]

open access: yes, 2015
A methodology for structural analysis simulations is presented that incorporates the distribution of mechanical propertiesalong the geometrical dimensions of injection-moulded amorphous polymer products.
Engels, Tom A.P.   +3 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Application of multi sensor data fusion based on Principal Component Analysis and Artificial Neural Network for machine tool thermal monitoring [PDF]

open access: yes, 2015
Due to the various heat sources on a machine tool, there exists a complex temperature distribution across its structure. This causes an inherent thermal hysteresis which is undesirable as it affects the systematic tool –to-workpiece positioning ...
Fletcher, Simon   +3 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Bloch oscillation of elastic waves in the graded lattice of 3D-printed hollow elliptical cylinders

open access: yes, 2018
We study the Bloch oscillation of elastic waves in a chain composed of hollow elliptical cylinders (HECs). These HECs are 3D-printed in different wall thicknesses and are arranged to form a graded chain.
Kim, Eunho   +3 more
core   +1 more source

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