Results 91 to 100 of about 2,309 (295)

Design and Implementation of a Stereo Vision System on an Innovative 6DOF Single-Edge Machining Device for Tool Tip Localization and Path Correction

open access: yesSensors, 2018
In the current meso cutting technology industry, the demand for more advanced, accurate and cheaper devices capable of creating a wide range surfaces and geometries is rising.
Luis López-Estrada   +5 more
doaj   +1 more source

Machine Learning Based Localization [PDF]

open access: yes, 2009
A vast majority of localization techniques proposed for sensor networks are based on triangulation methods in Euclidean geometry. They utilize the geometrical properties of the sensor network to infer the sensor locations. A fundamentally different approach is presented in this chapter.
Duc A. Tran   +2 more
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

On the chaotic nature of electro-discharge machining [PDF]

open access: yes, 2015
The long-accepted thermoelectric model for electro-discharge machining is being brought into question. Several experimental facts prompt the proposal of a new theory based on the effect of gap pollution on the ignition of discharges.
Sofroniou, Mark   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Quantitative robustness of localized support vector machines

open access: yesCommunications on Pure and Applied Analysis, 2020
The huge amount of available data nowadays is a challenge for kernel-based machine learning algorithms like SVMs with respect to runtime and storage capacities. Local approaches might help to relieve these issues and to improve statistical accuracy. It has already been shown that these local approaches are consistent and robust in a basic sense.
openaire   +3 more sources

Multi-point Clamping with Automatic Collision Avoidance for Aircraft Structural Parts Machining [PDF]

open access: yes, 2016
In order to solve the problem of machining motion collision between cutter and fixtures, a multi-point clamping system with automatic collision avoidance is proposed for aircraft structural parts.
Hou, Bo   +6 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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