Results 91 to 100 of about 2,247 (260)

Through-mask electrochemical machining of micro-dimple arrays with synchronization of power switching and cathode movements

Advances in Mechanical Engineering
Micro-dimple arrays with specific shapes and dimensions are crucial for reducing wear and vibration. Through-mask electrochemical machining (TMECM) using flexible cathodes removes materials based on anodic dissolution and allows for efficient processing ...
Feng Wang, Xinke Yuan, Tao Wang, Yiqing Wan, Yafeng He, Min Kang   +5 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Research on jet electrochemical machining with coaxial megasonic assistance

Ultrasonics Sonochemistry
In order to address the problem of poor localization in electrochemical machining (ECM), a coaxial megasonic assisted jet ECM method was proposed. Based on theoretical analysis, experiments were conducted to compare the effects of various electrolyte ...
Ke Zhai, Yongkang Liang, Tengnan Li, Shihao Ma, Liqun Du   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Adaptive Robotic Deburring of Molded Parts via 3D Vision and Tolerance-Constrained Non-Rigid Registration

Journal of Manufacturing and Materials Processing
This paper introduces an innovative automatic trajectory generation method for the robotic deburring of molded parts, effectively addressing challenges posed by burr defects and workpiece deformation common in casting and injection molding processes ...
Zuping Zhou, Zhilin Sun, Pengfei Luo
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Elevated-Temperature Tensile Behavior and Properties of Inconel 718 Fabricated by In-Envelope Additive–Subtractive Hybrid Manufacturing and Post-Process Precipitation Hardening

Journal of Manufacturing and Materials Processing
The present study focuses on advancing one of the most popular AM techniques, namely, laser powder bed fusion (LPBF) technology, which has the ability to produce complex geometry parts with minimum material waste but continues to face challenges in ...
Sheida Sarafan, Priti Wanjara, Roger Pelletier, Sila Ece Atabay, Javad Gholipour, Josh Soost, Robert Amos, Prakash Patnaik   +7 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Zr-modified TiAlSiN coatings regulate interfacial thermomechanics and primary shear-zone deformation during dry machining

Journal of Materials Research and Technology
This work clarifies how representative TiAlSi(Zr)N coating states influence tool-chip interfacial thermomechanics, tool-wear evolution, and primary shear-zone (PSZ) deformation during dry machining.
Ruihao Zhang, Kai Ma, Jinfu Zhao, Zhanqiang Liu, Bing Wang, Shequan Wang, Qinghua Song   +6 more
doaj   +1 more source